Computational analysis of the importance of flow synchrony for cardiac ventricular assist devices
Matt McCormick,David Nordsletten,Pablo Lamata,Nicolas P. Smith,Nicolas P. Smith,Nicolas P. Smith +5 more
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TLDR
In the simulations, increasing LVAD flow during myocardial contraction and decreasing it during diastole improved the mixing of blood in the LV cavity, and had the effect of partly homogenising work across the myocardium when the aortic valve did not open, reducing myocardian stress and thereby improving unloading.About:
This article is published in Computers in Biology and Medicine.The article was published on 2014-06-01 and is currently open access. It has received 21 citations till now. The article focuses on the topics: Ventricular assist device & Cardiac cycle.read more
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Multiphysics and multiscale modelling, data-model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics.
Radomir Chabiniok,Radomir Chabiniok,Vicky Y. Wang,Myrianthi Hadjicharalambous,Liya Asner,Jack Lee,Maxime Sermesant,Ellen Kuhl,Alistair A. Young,Philippe Moireau,Martyn P. Nash,Dominique Chapelle,David Nordsletten +12 more
TL;DR: Developments in computational cardiac modelling are reviewed and how their integration with medical imaging data is providing new pathways for translational cardiac modelling.
Journal ArticleDOI
Computational modeling of cardiac hemodynamics
Rajat Mittal,Jung Hee Seo,Vijay Vedula,Young Joon Choi,Hang Liu,H. Howie Huang,Saurabh Jain,Laurent Younes,Theodore P. Abraham,Richard T. George +9 more
TL;DR: The current status of computational modeling of cardiac hemodynamics as well as the emerging trends and challenges in cardiovascular health, computing, modeling and simulation and that are expected to play a key role in its future development are reviewed.
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Images as drivers of progress in cardiac computational modelling.
Pablo Lamata,Pablo Lamata,Ramón Casero,Valentina Carapella,S Niederer,Martin J. Bishop,Jürgen E. Schneider,Peter Kohl,Vicente Grau +8 more
TL;DR: How novel imaging technologies, or the innovative use and extension of established ones, integrate with computational models and drive novel insights into cardiac biophysics are reviewed.
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Multiphysics Computational Modeling in CHeart
Jack Lee,Andrew Cookson,Andrew Cookson,Ishani Roy,Eric Kerfoot,Liya Asner,G. Vigueras,Taha Sochi,Simone Deparis,Christian Michler,Nicolas P. Smith,David Nordsletten +11 more
TL;DR: This paper describes the infrastructural framework for generic multiphysics integration implemented in the software $\boldsymbol{\mathcal{C}}\mathbf{Heart}$, a finite-element code for biomedical research, and introduces the notion of topological interfaces which enable the evaluation of weak form integrals between mesh subregions of arbitrary finite- element bases' orders, types, and spatial dimensions.
Journal ArticleDOI
An efficient and accurate method for modeling nonlinear fractional viscoelastic biomaterials.
Will Zhang,Adela Capilnasiu,Gerhard Sommer,Gerhard Holzapfel,Gerhard Holzapfel,David Nordsletten,David Nordsletten +6 more
TL;DR: In this article, a numerical approximation to the Caputo derivative was proposed, which exploits a recurrence relation similar to those used to discretize classic temporal derivatives, giving a computational cost that is O( N T ) and a storage cost that was fixed over time.
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Journal ArticleDOI
Numerical analysis of blood flow in the heart
TL;DR: In this article, the authors extended previous work on the solution of the Navier-Stokes equations in the presence of moving immersed boundaries which interact with the fluid and introduced an improved numerical representation of the δ-function.
Journal Article
Heart-lung transplantation.
TL;DR: A broad overview of the various grounds upon which this difference is likely based and discuss recent advances in each area: 1) criteria for the selection of candidates and donors, 2) methods for ex-vivo preservation of donor organs, 3) technical execution of the operative procedure, and 4) prevention of postoperative infection as discussed by the authors.
Journal ArticleDOI
Conforming and nonconforming finite element methods for solving the stationary Stokes equations I
M. Crouzeix,P.-A. Raviart +1 more
TL;DR: Both conforming and nonconforming finite element methods are studied and various examples of simplicial éléments well suited for the numerical treatment of the incompressibility condition are given.
Journal ArticleDOI
Laminar structure of the heart: ventricular myocyte arrangement and connective tissue architecture in the dog
TL;DR: It is concluded that ventricular myocardium is not a uniformly branching continuum but a laminar hierarchy in which it is possible to identify three axes of material symmetry at any point.
Journal ArticleDOI
Mathematical model of geometry and fibrous structure of the heart.
TL;DR: These methods provide a compact and accurate anatomic description of the ventricles suitable for use in finite element stress analysis, simulation of cardiac electrical activation, and other cardiac field modeling problems.