Open AccessJournal Article
Consanguinity and blood group distribution in an Amish Isolate.
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This article is published in American Journal of Human Genetics.The article was published on 1968-11-01 and is currently open access. It has received 22 citations till now. The article focuses on the topics: Consanguinity.read more
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Review of cancer among 4 religious sects: Evidence that life-styles are distinctive sets of risk factors
TL;DR: All 4 religious groups considered in this paper have reduced overall rates of cancer, suggesting that the life-styles of all 4 groups have merit in terms of reducing the overall risk of cancer.
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Alzheimer's disease and apolipoprotein E-4 allele in an Amish population
Margaret A. Pericak-Vance,Christine Cole Johnson,J. B. Rimmler,Ann M. Saunders,L. C. Robinson,E. D'Hondt,Charles E. Jackson,Jonathan L. Haines +7 more
TL;DR: It is suggested that the lower frequency of dementia in the Amish may be partially explained by the decreased frequency of the APOE−4 allele in this population, and that the inbred nature of this pedigree, with its strong clustering of cases contrasted against the lower frequencies of dementia, indicates that additional genetic factors influence late‐onset AD.
Journal ArticleDOI
A genome-wide linkage analysis of dementia in the Amish†
Daniel W. Hahs,Jacob L. McCauley,Amy E. Crunk,Lynne L. McFarland,Perry C. Gaskell,Lan Jiang,Susan H. Slifer,Jeffery M. Vance,William K. Scott,Kathleen A. Welsh-Bohmer,Stephanie Johnson,Charles E. Jackson,Margaret A. Pericak-Vance,Jonathan L. Haines +13 more
TL;DR: A genome‐wide genetic linkage screen using individuals from the relatively isolated, genetically homogeneous, Amish population identifies regions of the genome that may be involved in a subset of dementia patients, in particular the North American Amish community.
Journal ArticleDOI
Population studies and the Old Order Amish.
TL;DR: Populations of Old Order Amish, living in Pennsylvania, Ohio and Indiana, and isolated by their strict religious views, have provided human geneticists with a rich source of data.
Journal ArticleDOI
Genetic studies in Paraguay: blood group, red cell, and serum genetic patterns of the Guayaki and Ayore Indians, Mennonite settlers, and seven other Indian tribes of the Paraguayan Chaco.
TL;DR: Differences among groups studied, and between Paraguayan and other Amerinds emphasize importance of genetic drift and founder principle.