Deficient Fear Conditioning in Psychopathy A Functional Magnetic Resonance Imaging Study
Niels Birbaumer,Ralf Veit,Martin Lotze,Michael Erb,Christiane Hermann,Wolfgang Grodd,Herta Flor +6 more
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TLDR
This dissociation of emotional and cognitive processing may be the neural basis of the lack of anticipation of aversive events in criminal psychopaths.Abstract:
Context Psychopaths belong to a larger group of persons with antisocial personality disorder and are characterized by an inability to have emotional involvement and by the repeated violation of the rights of others. It was hypothesized that this behavior might be the consequence of deficient fear conditioning. Objective To study the cerebral, peripheral, and subjective correlates of fear conditioning in criminal psychopaths and healthy control subjects. Design An aversive differential pavlovian delay conditioning paradigm with slides of neutral faces serving as conditioned and painful pressure as unconditioned stimuli. Setting The Department of Medical Psychology at the University of Tubingen, Tubingen, Germany. Participants Ten male psychopaths as defined by the Hare Psychopathy Checklist–Revised and 10 age- and education-matched healthy male controls. The psychopaths were criminal offenders on bail and waiting for their trial or were on parole. The healthy controls were recruited from the community. Main Outcome Measures Brain activation based on functional magnetic resonance imaging, electrodermal responses, emotional valence, arousal, and contingency ratings. Results The healthy controls showed enhanced differential activation in the limbic-prefrontal circuit (amygdala, orbitofrontal cortex, insula, and anterior cingulate) during the acquisition of fear and successful verbal and autonomic conditioning. The psychopaths displayed no significant activity in this circuit and failed to show conditioned skin conductance and emotional valence ratings, although contingency and arousal ratings were normal. Conclusion This dissociation of emotional and cognitive processing may be the neural basis of the lack of anticipation of aversive events in criminal psychopaths.read more
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References
More filters
Journal ArticleDOI
Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain
Nathalie Tzourio-Mazoyer,B. Landeau,D. Papathanassiou,Fabrice Crivello,Octave Etard,Nicolas Delcroix,Bernard Mazoyer,Marc Joliot +7 more
TL;DR: An anatomical parcellation of the spatially normalized single-subject high-resolution T1 volume provided by the Montreal Neurological Institute was performed and it is believed that this tool is an improvement for the macroscopical labeling of activated area compared to labeling assessed using the Talairach atlas brain.
Journal ArticleDOI
Measuring emotion: The self-assessment manikin and the semantic differential
Margaret M. Bradley,Peter Lang +1 more
TL;DR: Reports of affective experience obtained using SAM are compared to the Semantic Differential scale devised by Mehrabian and Russell (An approach to environmental psychology, 1974), which requires 18 different ratings.
Journal ArticleDOI
Thresholding of statistical maps in functional neuroimaging using the false discovery rate.
TL;DR: This paper introduces to the neuroscience literature statistical procedures for controlling the false discovery rate (FDR) and demonstrates this approach using both simulations and functional magnetic resonance imaging data from two simple experiments.
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The Dark Triad of personality: Narcissism, Machiavellianism, and psychopathy
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Journal ArticleDOI
Empathy: Its ultimate and proximate bases.
TL;DR: The Perception-Action Model (PAM), together with an understanding of how representations change with experience, can explain the major empirical effects in the literature and can also predict a variety of empathy disorders.