Journal ArticleDOI
Delivery of drugs, proteins, and nucleic acids using inorganic nanoparticles.
David C. Luther,Rui Huang,Taewon Jeon,Xianzhi Zhang,Yi-Wei Lee,Harini Nagaraj,Vincent M. Rotello +6 more
TLDR
The structural and functional diversity of gold, silica, iron oxide, and lanthanide-based nanocarriers provide unrivalled control of nanostructural properties for effective transport of therapeutic cargos, overcoming biobarriers on the cellular and organismal level.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2020-06-29. It has received 127 citations till now. The article focuses on the topics: Nanocarriers.read more
Citations
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Mechanized Silica Nanoparticles: A New Frontier in Theranostic Nanomedicine
TL;DR: In this paper, the use of mesoporous silica nanoparticles (MSNPs) has been investigated for the delivery of bioactive agents within living tissue, where the payload "cargo" molecules can be stored within this robust domain, which is stable to a wide range of chemical conditions.
Journal ArticleDOI
Nanodelivery of nucleic acids
Bárbara B. Mendes,João Miguel de Oliveira Conniot,Aviram Avital,Dongbao Yao,Xingya Jiang,Xiang Zhou,Noga Sharf-Pauker,Yuling Xiao,Omer Adir,Haojun Liang,Jinjun Shi,Avi Schroeder,João Conde +12 more
TL;DR: Conde et al. as discussed by the authors discussed the design considerations of nucleic acid delivery nanoparticles, their extraordinary properties and the structure-function relationships of these nanomaterials with biological systems and diseased cells and tissues.
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Magnetic nanoparticles for cancer theranostics: Advances and prospects
TL;DR: A review of magnetic nanoparticles in cancer theranostics can be found in this article, where the authors consolidate the recent improvements in MNPs for clinical applications as well as discuss the future research prospects and potential of MNPs.
Journal ArticleDOI
Porous MOF Microneedle Array Patch with Photothermal Responsive Nitric Oxide Delivery for Wound Healing
Shun Yao,Yuetong Wang,Yuetong Wang,Junjie Chi,Junjie Chi,Yu Yunru,Yu Yunru,Yuanjin Zhao,Yuanjin Zhao,Yuan Luo,Yongan Wang +10 more
TL;DR: In this article, a novel porous metal-organic framework (MOF) microneedle (MN) patch enabling photothermal-responsive nitric oxide (NO) delivery for promoting diabetic wound healing is presented.
Journal ArticleDOI
Tunable morphology and functionality of multicomponent self-assembly: A review
TL;DR: In this article, the tuning of morphology and functionality of multicomponent co-assembly was discussed according to the purpose of their mixing in the following three aspects separately: (1) one of the components can self-assemble individually, the other added components can tune the morphology and functionalities of the assemblies, (2) all of the component can self assemble individually but the mixture can strength the assemblies or generate new functionalities, and (3) none of the constituent can self assemble individually, but the mixtures can selfassemble into novel properties.
References
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Self-assembled monolayers of thiolates on metals as a form of nanotechnology.
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A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials
TL;DR: A method for assembling colloidal gold nanoparticles rationally and reversibly into macroscopic aggregates by using the specificity of DNA interactions to direct the interactions between particles of different size and composition is described.
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Stimuli-responsive nanocarriers for drug delivery
TL;DR: Recent advances in the design of nanoscale stimuli-responsive systems that are able to control drug biodistribution in response to specific stimuli, either exogenous (variations in temperature, magnetic field, ultrasound intensity, light or electric pulses) or endogenous (changes in pH, enzyme concentration or redox gradients).
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Recent advances with liposomes as pharmaceutical carriers.
TL;DR: For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
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Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles
TL;DR: A highly selective, colorimetric polynucleotide detection method based on mercaptoalkyloligonucleotide-modified gold nanoparticle probes is reported, which can detect about 10 femtomoles of an oligonucleotide.