Journal ArticleDOI
Development and validation of the self-administered Food Allergy Quality of Life Questionnaire for adolescents
Bertine M. J. Flokstra-de Blok,Audrey DunnGalvin,Berber Vlieg-Boerstra,Joanne N.G. Oude Elberink,Eric J. Duiverman,Jonathan O'b Hourihane,Anthony E.J. Dubois +6 more
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TLDR
The FAQLQ-TF is the first self-administered, disease-specific HRQL questionnaire for adolescents with food allergy and has good construct validity and excellent internal consistency and discriminates between adolescents who differ in the number of food allergies.Abstract:
Background Food allergy can affect health-related quality of life (HRQL). Currently, no validated, self-administered, disease-specific HRQL questionnaire for adolescents with food allergy exists. Objective We sought to develop and validate the Food Allergy Quality of Life Questionnaire–Teenager Form (FAQLQ-TF) in the Dutch language. Methods Ten adolescents (13-17 years) with food allergy were interviewed and generated 166 HRQL items. The most important items were identified by 51 adolescents with food allergy by using the clinical impact method, resulting in the FAQLQ-TF containing 28 items (score range: 1 "no impairment" to 7 "maximal impairment"). The FAQLQ-TF, the Food Allergy Independent Measure, and a generic HRQL questionnaire (CHQ-CF87) were sent to 98 adolescents with food allergy for cross-sectional validation of the FAQLQ-TF. Results Construct validity was assessed based on the correlation between the FAQLQ-TF and the Food Allergy Independent Measure (ρ = 0.57, P 2 food allergies: total FAQLQ-TF score, 4.3 vs 3.5; P = 0.037) but did not discriminate between those who did or did not have reported anaphylaxis. The FAQLQ-TF correlated weakly with 6 of the 11 CHQ-CF87 scales, demonstrating convergent/discriminant validity. Conclusion The FAQLQ-TF is the first self-administered, disease-specific HRQL questionnaire for adolescents with food allergy. It has good construct validity and excellent internal consistency and discriminates between adolescents who differ in the number of food allergies. The FAQLQ-TF is short and easy to use and might therefore be a useful tool in clinical research.read more
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Journal ArticleDOI
The psychosocial impact of food allergy and food hypersensitivity in children, adolescents and their families: a review.
TL;DR: The psychosocial impact of food allergy and food hypersensitivity in children, adolescents and their families: a review is a review.
Journal ArticleDOI
Health-related quality of life of food allergic patients: Comparison with the general population and other diseases
B. M. J. Flokstra-de Blok,Anthony E.J. Dubois,Berber Vlieg-Boerstra,J. N. G. Oude Elberink,H. Raat,Audrey DunnGalvin,J. OâB. Hourihane,E. J. Duiverman +7 more
TL;DR: In this article, the authors compared generic health-related quality of life (HRQL) of food allergic patients from childhood to adulthood with that of the general population or patients with other chronic diseases.
Journal ArticleDOI
Assessment of psychological distress among children and adolescents with food allergy
TL;DR: Assessment of attitudes toward food allergy and maternal anxiety were associated with child distress for children 8 to 17 years old, and targets for prevention of distress are suggested.
Journal ArticleDOI
Efficacy, Safety, and Quality of Life in a Multicenter, Randomized, Placebo-Controlled Trial of Low-Dose Peanut Oral Immunotherapy in Children with Peanut Allergy
Katharina Blumchen,Katharina Blumchen,Valérie Trendelenburg,Frank Ahrens,A. Gruebl,Eckard Hamelmann,Eckard Hamelmann,Gesine Hansen,Andrea Heinzmann,Katja Nemat,Thomas Holzhauser,Martin Roeder,L Rosenfeld,Oliver Hartmann,Bodo Niggemann,Kirsten Beyer +15 more
TL;DR: Low-dose OIT is a promising, effective, and safe treatment option for peanut-allergic children, leading to improvement in QOL, a low BOT, and immunologic changes showing tolerance development.
Journal ArticleDOI
Precautionary allergen labelling: Perspectives from key stakeholder groups
Audrey DunnGalvin,C. H. Chan,René W.R. Crevel,Kate Grimshaw,Roland Poms,Sabine Schnadt,S.L. Taylor,Paul Turner,Katrina J. Allen,Marie-Paule Austin,Athanasia Baka,Joseph L. Baumert,Sabine Baumgartner,Kirsten Beyer,Luca Bucchini,Montserrat Fernandez-Rivas,Kirsten Grinter,Geert F. Houben,J. O. B. Hourihane,Fiona Kenna,Astrid G. Kruizinga,Gideon Lack,Charlotte Bernhard Madsen,E. N. Clare Mills,Nikolaos G. Papadopoulos,Nikolaos G. Papadopoulos,Anton J. Alldrick,Lynne Regent,Robin Sherlock,Jean-Michel Wal,Graham Roberts,Graham Roberts,Graham Roberts +32 more
TL;DR: This review aims to summarize the perspectives of all the key stakeholders (including clinicians, patients, food industry and regulators), with the aim of defining common health protection and risk minimization goals.
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