Journal ArticleDOI
Diagnostic Accuracy of Conventional Versus Sonography-Guided Fine-Needle Aspiration Biopsy of Thyroid Nodules
TLDR
It is demonstrated that SG-FNAB allows a more precise and adequate sampling of thyroid nodular lesions and is associated with a lower rate of false-negatives, thus improving global diagnostic accuracy in the preoperative selection of thyroid cancer.Abstract:
Fine-needle aspiration biopsy (FNAB) is an accurate, slightly invasive, and safe method for the preoperative diagnosis of thyroid nodules. Recently, ultrasound guidance has been suggested as a valuable aid to enhance FNAB diagnostic performance. In this study, we have compared diagnostic accuracy of conventional FNAB (C-FNAB) versus sonography-guided FNAB (SG-FNAB) on a large sample population of 9683 patients with thyroid nodules. Over a 15-year period, 4986 patients were investigated by C-FNAB and 4697 underwent SG-FNAB. A valid cytological diagnosis was obtained in 85.9% of C-FNAB and in 91.5% of SG-FNAB cases, allowing detection of thyroid cancer in 1.6% and 2.1% of patients, respectively. The indeterminate pattern of follicular neoplasia was observed in 238 C-FNAB (5%) and in 272 (5.4%) SG-FNAB nodules. Specimens were cytologically inadequate in 433 C-FNAB (8.7%), but only in 167 SG-FNAB cases (3.5%). A total of 535 C-FNAB and 540 SG-FNAB nodules underwent surgery. False-negative results occurred in ...read more
Citations
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Journal ArticleDOI
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TL;DR: Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
Journal ArticleDOI
Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
David S. Cooper,Gerard M. Doherty,Bryan R. Haugen,Richard T. Kloos,Stephanie L. Lee,Susan J. Mandel,Ernest L. Mazzaferri,Bryan McIver,Furio Pacini,Martin Schlumberger,Steven I. Sherman,David L. Steward,R. Michael Tuttle +12 more
TL;DR: Evidence-based recommendations in response to the appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
Journal ArticleDOI
Management guidelines for patients with thyroid nodules and differentiated thyroid cancer.
Journal ArticleDOI
Clinical practice. The thyroid nodule.
TL;DR: Improvement of existing tests or the addition of new tests for evaluating thyroid nodules will aid in distinguishing between benign and malignant thyroid nodule.
Journal ArticleDOI
Management of thyroid nodules detected at US: Society of radiologists in ultrasound consensus conference statement
Mary C. Frates,Carol B. Benson,J. William Charboneau,Edmund S. Cibas,Orlo H. Clark,Beverly G. Coleman,John J. Cronan,Peter M. Doubilet,Douglas B. Evans,John R. Goellner,Ian D. Hay,Barbara S. Hertzberg,Charles M. Intenzo,R. Brooke Jeffrey,Jill E. Langer,P. Reed Larsen,Susan J. Mandel,William D. Middleton,Carl C. Reading,Steven I. Sherman,Franklin N. Tessler +20 more
TL;DR: The recommendations in this consensus statement, which are based on analysis of the current literature and common practice strategies, are thought to represent a reasonable approach to thyroid nodular disease.
References
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Journal ArticleDOI
A 2dvEv- bit distributed algorithm for the directed Euler trail problem
Wen-Huei Chen,Chuan Yi Tang +1 more
TL;DR: The algorithm can be used as a building block for solving other distributed graph problems, and can be slightly modified to run on a strongly-connected diagraph for generating the existent Euler trail or to report that no Euler trails exist.
Journal ArticleDOI
Management of a Solitary Thyroid Nodule
TL;DR: This review describes a strategy for the treatment of clinically euthyroid patients who have a solitary thyroid nodule that prevents unnecessary testing while identifying the few patients who require therapy.
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Fine-Needle Aspiration Biopsy of the Thyroid: An Appraisal
Hossein Gharib,John R. Goellner +1 more
TL;DR: The utility and limitations of fine-needle aspiration biopsy in the evaluation and management of thyroid nodules are examined by reviewing studies reported in the literature from 1982 to 1991 and using 12 years of experience with more than 11 000 biopsies to offer a reasoned approach to the management of nodular thyroid disease.
Journal ArticleDOI
Natural history, treatment, and course of papillary thyroid carcinoma.
TL;DR: The data strongly support the use of more extensive initial surgery in class I and II patients with tumors more than 1 cm in size as well as postoperative radioactive 131I ablation of thyroid remnant tissue.
Impact on Thyroid Practice and Cost of Care
TL;DR: It is suggested that fine-needle aspiration biopsy provides valuable information to assist in the selection for surgery of patients with solitary thyroid nodules, and appears to be safe, reliable, and cost-effective.