Dietary acid reduction with fruits and vegetables or bicarbonate attenuates kidney injury in patients with a moderately reduced glomerular filtration rate due to hypertensive nephropathy.
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TLDR
A reduction in dietary acid decreased kidney injury in patients with moderately reduced eGFR due to hypertensive nephropathy and that with fruits and vegetables was comparable to sodium bicarbonate, andruits and vegetables appear to be an effective kidney protective adjunct to blood pressure reduction and angiotensin-converting enzyme inhibition in hypertensive and possibly other nephrostathies.About:
This article is published in Kidney International.The article was published on 2012-01-01 and is currently open access. It has received 265 citations till now. The article focuses on the topics: Kidney disease & Hypertensive Nephropathy.read more
Citations
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KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 Update
T. Alp Ikizler,Jerrilynn D. Burrowes,Laura Byham-Gray,Katrina L. Campbell,Juan Jesus Carrero,Winnie Chan,Denis Fouque,Allon N. Friedman,Sana Ghaddar,D. Jordi Goldstein-Fuchs,George A. Kaysen,Joel D. Kopple,Daniel Teta,Angela Yee-Moon Wang,Lilian Cuppari +14 more
TL;DR: The 2020 update to the KDOQI Clinical Practice Guideline for Nutrition in CKD provides comprehensive up-to-date information on the understanding and care of patients with chronic kidney disease (CKD), especially in terms of their metabolic and nutritional milieu for the practicing clinician and allied health care workers.
Journal ArticleDOI
Chronic Kidney Disease Diagnosis and Management: A Review
TL;DR: Optimal management of CKD includes cardiovascular risk reduction, treatment of albuminuria, avoidance of potential nephrotoxins, and adjustments to drug dosing (eg, many antibiotics and oral hypoglycemic agents).
Journal ArticleDOI
Nutritional Management of Chronic Kidney Disease
TL;DR: The nutritional status of patients with chronic kidney disease is generally compromised and requires dietary adjustments, and several aspects of the nutritional management of chronic kidneys disease in adults are considered.
Journal ArticleDOI
A Comparison of Treating Metabolic Acidosis in CKD Stage 4 Hypertensive Kidney Disease with Fruits and Vegetables or Sodium Bicarbonate
TL;DR: Fruits and vegetables improve metabolic acidosis and reduce kidney injury in stage 4 CKD without producing hyperkalemia, and one year of fruits and vegetables or NaHCO3 yielded eGFR that was not different, was associated with higher-than-baseline PTCO2, and was associatedWith lower- than-Baseline urine indices of kidney injury.
Journal ArticleDOI
Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate
TL;DR: Dietary alkali treatment of metabolic acidosis in CKD that is less severe than that for which KDOQI recommends therapy reduces kidney angiotensin II activity and preserves eGFR.
References
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated, and empathy builds trust and is a potent motivator.
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Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet
Frank M. Sacks,Laura P. Svetkey,William M. Vollmer,Lawrence J. Appel,George A. Bray,David W. Harsha,Eva Obarzanek,Paul R. Conlin,E R Miller rd,Denise G. Simons-Morton,Njeri Karanja,Pao-Hwa Lin +11 more
TL;DR: The effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is rich in vegetables, fruits, and low-fat dairy products, in persons with and in those without hypertension is studied.
Journal ArticleDOI
Prevalence of Chronic Kidney Disease in the United States
Josef Coresh,Elizabeth Selvin,Lesley A. Stevens,Jane Manzi,John W. Kusek,Paul W. Eggers,Frederick Van Lente,Andrew S. Levey +7 more
TL;DR: The prevalence of CKD in the United States in 1999-2004 is higher than it was in 1988-1994 and this increase is partly explained by the increasing prevalence of diabetes and hypertension and raises concerns about future increased incidence of kidney failure and other complications.
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The Effects of Dietary Protein Restriction and Blood-Pressure Control on the Progression of Chronic Renal Disease
Saulo Klahr,Andrew S. Levey,Gerald J. Beck,Arlene W. Caggiula,Lawrence G. Hunsicker,John W. Kusek,Gary E. Striker +6 more
TL;DR: Restricting protein intake and controlling hypertension delay the progression of renal disease in animals and in patients with various chronic renal diseases.
Journal ArticleDOI
Pathophysiology of Progressive Nephropathies
Giuseppe Remuzzi,Tullio Bertani +1 more
TL;DR: In patients with renal diseases characterized by proteinuria, the initial insult to the kidney is usually followed by a progressive decline in the glomerular filtration rate, which is thought to be due to changes in renal hemodynamics initiated by the loss of nephrons.