Journal ArticleDOI
Distribution of serum lipoproteins of selected vertebrates
TLDR
Agarose gel electrophoresis was performed on the sera of thirty-six mammals, reptiles, amphibians, fish and birds, and the quantitative distribution of the lipoprotein classes in each animal was determined.Abstract:
1 1 Agarose gel electrophoresis was performed on the sera of thirty-six mammals, reptiles, amphibians, fish and birds, and the quantitative distribution of the lipoprotein classes in each animal was determined 2 2 Pig, opossum and garter snake sera seem to contain large amounts of low density lipoprotein, the lipoprotein class which is of primary interest in atherosclerosis research These animals also have serum cholesterol values similar to humans 3 3 Agarose gel electrophoresis proved an excellent method for determining lipoprotein distributions, but the electrophoretic mobilities of the lipoproteins appear to be unsuitable for lipoprotein classificationread more
Citations
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Book ChapterDOI
Lipoprotein Metabolism1 1In preparation of this study, Dr. Eisenberg was supported in part through the Special Foreign Currency Program of the National Library of Medicine, National Institutes of Health, Public Health Service, U. S. Department of Health, Education, and Welfare, Bethesda, Maryland, under an agreement with the Israel Journal of Medical Sciences, Jerusalem, Israel.
Shlomo Eisenberg,Robert I. Levy +1 more
Journal ArticleDOI
Distribution and characterization of the serum lipoproteins and apoproteins in the mouse, Mus musculus.
TL;DR: The presence of murine apolipoproteins analogous to human apoB and apoE was confirmed by the immunological cross-reactivities of VLDL and LDL with monospecific antisera to the human proteins.
Journal ArticleDOI
Biochemical Aspects of Lipid Storage and Utilization in Animals
TL;DR: Complete, quantitative data on the mechanisms and rates of lipid digestion, synthesis, transport and utilization are available for only a very few metazoans, which would seem to be a very fertile field for comparative physiologists.
Journal ArticleDOI
Safety evaluation of phytosterol esters. Part 2. Subchronic 90-day oral toxicity study on phytosterol esters--a novel functional food.
P.A Hepburn,S.A. Horner,M. Smith +2 more
TL;DR: A nominal PE concentration of 8.1% was considered to be the no-observed-adverse- effect level (NOAEL) following daily oral administration to rats for 90 days, equivalent to a dose of 6.6g/kg body weight/day PE or 4.1 g/kg/day phytosterol.
References
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Journal ArticleDOI
The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
TL;DR: The relatively low density of the lipoproteins was utilized by Lindgren, Elliott, and Gofman to separate them from the other serum proteins by ultracentrifugal flotation, and quantitation was subsequently performed by refractometric methods in the analytical ultracentRifuge.
Journal ArticleDOI
Electrophoretic separation of plasma lipoproteins in agarose gel
TL;DR: The clearcut separation of lipoproteins by this method will facilitate the classification of hyperlipoproteinemias and improve quantitative estimates oflipoprotein distribution.
Journal ArticleDOI
Molecular complexes in the isolation and characterization of plasma lipoproteins.
David G. Cornwell,Fred A. Kruger +1 more
TL;DR: Methods employing complex formation for the isolation and quantitation of plasma lipoproteins evaluated and turbidimetric procedures comparable in some ways to the older thymol and phenol turbidity tests for the estimation of y-globulins and lipiproteins are evaluated.
Journal ArticleDOI
Histological and immunofluorescent studies on the evolution of the human atheromatous plaque
K.W. Walton,N. Williamson +1 more
TL;DR: In uncomplicated plaques, specific immunofluorescence was obtained with antisera specific for low-density lipoproteins at all stages of development of plaques and in plaques complicated by superimposed thrombosis or platelet deposition.
Journal ArticleDOI
A study of the immunohistochemical localization of serum lipoproteins and other plasma proteins in human atherosclerotic lesions.
TL;DR: Fluorescent anti-LD lipoproteins consistently stained diseased areas of aortic intima where lipid was revealed by Oil red O stain and the fluorescent anti-albumin and anti-gamma globulin stained none of the lesions.
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