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Journal ArticleDOI

DNA breakage by resveratrol and Cu(II): reaction mechanism and bacteriophage inactivation.

Aamir Ahmad, +3 more
- 01 Jun 2000 - 
- Vol. 154, Iss: 1, pp 29-37
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TLDR
It is shown that resveratrol catalyzes the reduction of Cu(II) to Cu(I), which is accompanied by the formation of 'oxidized product(s)' of resver atrol, which in turn also appear to catalyze the Reduction of Cu (II).
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This article is published in Cancer Letters.The article was published on 2000-06-01. It has received 119 citations till now. The article focuses on the topics: Resveratrol.

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Role of Resveratrol in Prevention and Therapy of Cancer: Preclinical and Clinical Studies

TL;DR: In vivo, resveratrol blocks the multistep process of carcinogenesis at various stages: it blocks carcinogen activation by inhibiting aryl hydrocarbon-induced CYP1A1 expression and activity, and suppresses tumor initiation, promotion and progression.
Journal ArticleDOI

Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties.

TL;DR: The current knowledge regarding potential dietary flavonoid/phenolic-induced toxicity concerns, including their pro-oxidant activity, mitochondrial toxicity (potential apoptosis-inducing properties), and interactions with drug-metabolizing enzymes are summarized.
Journal ArticleDOI

Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms

TL;DR: There is increasing evidence that resveratrol exhibits pro-oxidant activity under certain experimental conditions, causing oxidative DNA damage that may lead to cell cycle arrest or apoptosis.
Journal ArticleDOI

Virulent bacteriophage for efficient biocontrol of Listeria monocytogenes in ready-to-eat foods.

TL;DR: It is demonstrated that virulent broad-host-range phages, such as A511 and P100, can be very effective for specific biocontrol of L. monocytogenes in contamination-sensitive RTE foods.
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A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol.

TL;DR: Recent advances that have provided new insights into the molecular mechanisms underlying the promising properties of resveratrol include cyclooxygenase, nitric oxide synthase and cytochrome P450 inhibition, as well as cell cycle effects, apoptosis modulation and hormonal activity.
References
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Book

Molecular Cloning: A Laboratory Manual

TL;DR: Molecular Cloning has served as the foundation of technical expertise in labs worldwide for 30 years as mentioned in this paper and has been so popular, or so influential, that no other manual has been more widely used and influential.
Journal ArticleDOI

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

TL;DR: It is suggested that resveratrol, a common constituent of the human diet, merits investigation as a potential cancer chemopreventive agent in humans.
Journal ArticleDOI

Colorimetric Methods Of Analysis

TL;DR: In this article, colorimetric methods of analysis were used for analysis of color data in the context of analysis of the color spectrum of a color-imetric method of analysis.
Journal ArticleDOI

Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor

TL;DR: It is concluded that resveratrol is a phytoestrogen and that it exhibits variable degrees of estrogen receptor agonism in different test systems, which broaden the spectrum of its biological actions and may be relevant to the reported cardiovascular benefits of drinking wine.
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