Patent
Droplet actuator analyzer with cartridge
Gregory F. Smith,Ryan A. Sturmer,Philip Y. Paik,Vijay Srinivasan,Michael G. Pollack,Vamsee K. Pamula,Keith R. Brafford,Richard M. West +7 more
TLDR
In this article, a sample analyzer is provided and includes an analyzer unit comprising electronic or optical receiving means, a cartridge comprising self-contained droplet handling capabilities, and a wherein the cartridge is coupled to the analyzer by a means which aligns electronic and/or optical outputs from the cartridge with electronic or optic receiving means on the analyser unit.Abstract:
A droplet actuator with cartridge is provided According to one embodiment, a sample analyzer is provided and includes an analyzer unit comprising electronic or optical receiving means, a cartridge comprising self-contained droplet handling capabilities, and a wherein the cartridge is coupled to the analyzer unit by a means which aligns electronic and/or optical outputs from the cartridge with electronic or optical receiving means on the analyzer unit According to another embodiment, a sample analyzer is provided and includes a sample analyzer comprising a cartridge coupled thereto and a means of electrical interface and/or optical interface between the cartridge and the analyzer, whereby electrical signals and/or optical signals may be transmitted from the cartridge to the analyzerread more
Citations
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Patent
Apparatuses and methods for manipulating droplets on a printed circuit board
TL;DR: The use of soldermask as an electrode insulator for droplet manipulation as well as techniques for adapting other traditional PCB layers and materials for droplets-based microfluidics are also disclosed in this article.
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Sample Processing Droplet Actuator, System and Method
TL;DR: In this paper, a stamping device including a droplet microactuator is provided and includes: (a) a first plate including a path or network of control electrodes for transporting droplets on a surface thereof; (b) a second plate mounted in a substantially parallel orientation with respect to the first plate providing an interior volume between the plates, the second plate including one or more stamping ports for transporting some portion or all of a liquid from the interior volume to an exterior location; (c) a port for introducing fluid into the interior space between the two plates; and (
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Droplet-based affinity assays
TL;DR: In this paper, a method of detecting a target analyte in a sample is provided, wherein the method includes: (a) executing droplet operations to combine affinity-based assay reagents on a droplet microactuator with a sample potentially comprising the target analyser to generate a signal indicative of the presence, absence and/or quantity of analyte; and (b) detecting the signal, where the signal corresponds to the presence or absence or quantity of the analyte.
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Capacitance detection in a droplet actuator
TL;DR: In this article, a method, circuit and apparatus for detecting capacitance on a droplet actuator, inter alia, for determining the presence, partial presence or absence of an active droplet at an electrode on the actuator is presented.
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Droplet actuator devices and methods employing magnetic beads
TL;DR: In this article, a method of providing a droplet in contact with a magnetically responsive bead and having a reduced quantity of a substance was proposed, where the beads are magnetically immobilized at a location which is at a distance from a target droplet splitting zone.
References
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