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Open AccessJournal ArticleDOI

Early life adversity reduces stress reactivity and enhances impulsive behavior: implications for health behaviors.

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TLDR
This model provides a pathway from early life adversity to low stress reactivity that forms a basis for risky behaviors and poor health outcomes.
About
This article is published in International Journal of Psychophysiology.The article was published on 2013-10-01 and is currently open access. It has received 239 citations till now. The article focuses on the topics: Reactivity (psychology) & Impulsivity.

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Citations
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Biological embedding of childhood adversity: from physiological mechanisms to clinical implications.

TL;DR: Reviewed evidence has important implications for clinical practice, biomedical research, and work across other sectors relevant to public health and child wellbeing, and calls on researchers, clinicians, policymakers, and other practitioners to act upon evidence.
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Annual Research Review: Early adversity, the hypothalamic-pituitary-adrenocortical axis, and child psychopathology.

TL;DR: A better understanding of individual differences in the adversity-HPA axis-psychopathology associations will require continued work addressing how multiple biological and behavioral systems work in concert to shape development.
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The other side of the coin: blunted cardiovascular and cortisol reactivity are associated with negative health outcomes.

TL;DR: Further evidence is presented implicating that cardiovascular and stress hormone responses to acute stress at the other end of the response spectrum can also be considered a pathway to ill health.
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The behavioural, cognitive, and neural corollaries of blunted cardiovascular and cortisol reactions to acute psychological stress.

TL;DR: A model of blunted stress reactivity is proffer, suggesting some individuals may be characterised by a broad failure in cardiovascular and cortisol responding to both stress and reward, reflecting fronto-limbic dysregulation.
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Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene.

TL;DR: These findings robustly demonstrate aberrant interactions of stress and reward networks after early-life adversity and suggest mechanistic roles for Crh-expressing amygdala neurons in emotional deficits portending major neuropsychiatric disorders.
References
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Book

Stress, appraisal, and coping

TL;DR: In this paper, the authors present a detailed theory of psychological stress, building on the concepts of cognitive appraisal and coping, which have become major themes of theory and investigation in psychology.
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Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study

TL;DR: For example, this article found a strong relationship between the breadth of exposure to abuse or household dysfunction during childhood and multiple risk factors for several of the leading causes of death in adults.
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Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

TL;DR: Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup.
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The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory Setting

TL;DR: The results suggest that gender, genetics and nicotine consumption can influence the individual's stress responsiveness to psychological stress while personality traits showed no correlation with cortisol responses to TSST stimulation.
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Role of Genotype in the Cycle of Violence in Maltreated Children

TL;DR: In this paper, a large sample of male children from birth to adulthood was studied to determine why some children who are maltreated grow up to develop antisocial behavior, whereas others do not.
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