Journal ArticleDOI
Effects of ultra-processed foods on the microbiota-gut-brain axis: The bread-and-butter issue.
TLDR
In this paper , a review of the link between UPF ingredients and the MGB axis is presented, and the authors emphasize that food additives including emulsifiers, artificial sweeteners, colorants, and preservatives interact with the gut microbiota and their possible effects on altering the brain and behavior.About:
This article is published in Food Research International.The article was published on 2023-05-01. It has received 1 citations till now. The article focuses on the topics: Medicine & Gut flora.read more
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Nutrient Inadequacy in Korean Young Adults with Depression: A Case Control Study
TL;DR: In this paper , a case-control study examined the association between nutrition and depression in young Korean adults and found that the depression group consumed less energy and nutrients, and the difference was more pronounced in men.
References
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Journal ArticleDOI
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve.
Javier A. Bravo,Paul Forsythe,Marianne V. Chew,Emily Escaravage,Hélène M. Savignac,Timothy G. Dinan,John Bienenstock,John F. Cryan +7 more
TL;DR: Chronic treatment with L. rhamnosus induced region-dependent alterations in GABAB1b mRNA in the brain with increases in cortical regions and concomitant reductions in expression in the hippocampus, amygdala, and locus coeruleus, in comparison with control-fed mice, highlighting the important role of bacteria in the bidirectional communication of the gut–brain axis.
Journal ArticleDOI
Host microbiota constantly control maturation and function of microglia in the CNS
Daniel Erny,Anna Lena Hrabě de Angelis,Diego Jaitin,Peter Wieghofer,Ori Staszewski,Eyal David,Hadas Keren-Shaul,Tanel Mahlakõiv,Kristin Jakobshagen,Thorsten Buch,Vera Schwierzeck,Olaf Utermöhlen,Eunyoung Chun,Wendy S. Garrett,Kathy D. McCoy,Andreas Diefenbach,Peter Staeheli,Bärbel Stecher,Ido Amit,Marco Prinz +19 more
TL;DR: It is determined that short-chain fatty acids (SCFA), microbiota-derived bacterial fermentation products, regulated microglia homeostasis and mice deficient for the SCFA receptor FFAR2 mirroredmicroglia defects found under GF conditions, suggesting that host bacteria vitally regulate microglian maturation and function.
Journal ArticleDOI
Introduction to the human gut microbiota
Elizabeth Thursby,Nathalie Juge +1 more
TL;DR: This review summarises the current understanding of the development and composition of the human GI microbiota, and its impact on gut integrity and host health, underlying the need for mechanistic studies focusing on host–microbe interactions.
Journal ArticleDOI
Artificial sweeteners induce glucose intolerance by altering the gut microbiota
Jotham Suez,Tal Korem,David Zeevi,Gili Zilberman-Schapira,Christoph A. Thaiss,Ori Maza,David Israeli,Niv Zmora,Shlomit Gilad,Adina Weinberger,Yael Kuperman,Alon Harmelin,Ilana Kolodkin-Gal,Hagit Shapiro,Zamir Halpern,Eran Segal,Eran Elinav +16 more
TL;DR: It is demonstrated that consumption of commonly used NAS formulations drives the development of glucose intolerance through induction of compositional and functional alterations to the intestinal microbiota, thereby calling for a reassessment of massive NAS usage.
Journal ArticleDOI
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
Benoit Chassaing,Omry Koren,Julia K. Goodrich,Angela C. Poole,Shanthi Srinivasan,Ruth E. Ley,Andrew T. Gewirtz +6 more
TL;DR: Results support the emerging concept that perturbed host–microbiota interactions resulting in low-grade inflammation can promote adiposity and its associated metabolic effects and suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.