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Journal ArticleDOI

Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculation: a double-blind, placebo controlled study.

Sae Chul Kim, +1 more
- 01 Feb 1998 - 
- Vol. 159, Iss: 2, pp 425-427
TLDR
In men with premature ejaculation clomipramine was the most useful drug in terms of efficacy and treatment with sertraline was nearly as effective and had a lower incidence of side effects.
About
This article is published in The Journal of Urology.The article was published on 1998-02-01. It has received 147 citations till now. The article focuses on the topics: Intravaginal ejaculation latency time & Premature ejaculation.

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Citations
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Journal ArticleDOI

Disorders of Orgasm and Ejaculation in Men

TL;DR: The recommendations concerning state-of-the-art knowledge of disorders of orgasm and ejaculation represent the opinion of seven experts from seven countries developed in a process over a 2-year period.
Journal ArticleDOI

The Neurobiological Approach to Premature Ejaculation

TL;DR: Psychopharmacological treatment studies, animal research data and stopwatch assessments in men with rapid (premature) ejaculation indicate that lifelong rapid ejaculation is a neurobiological phenomenon related to central serotonergic neurotransmission and likely influenced by hereditary fac...
Book ChapterDOI

Male Sexual Behavior

TL;DR: Major areas controlling sexual motivation and performance in males include the mesolimbic dopamine (DA) system, the medial preoptic area (MPOA), the amygdala, and the bed nucleus of the stria terminalis (BST).
Journal ArticleDOI

Relevance of methodological design for the interpretation of efficacy of drug treatment of premature ejaculation: a systematic review and meta-analysis.

TL;DR: At daily treatment, the overall efficacy of paroxetine, clomipramine, sertraline and fluoxetines is comparable, but paroxettine exerts the strongest ejaculation delay.
References
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Journal ArticleDOI

Paroxetine treatment of premature ejaculation: a double-blind, randomized, placebo-controlled study.

TL;DR: Patients treated with paroxetine had significantly greater clinical improvement than the patients given placebo.
Journal ArticleDOI

Effects of Psychotropic Drugs on Human Erection and Ejaculation

TL;DR: An understanding of the neurobiological substrate of human sexuality may assist clinicians in choosing psychotropic agents with minimal adverse effects on sexual behavior and may also contribute to the development of pharmacological interventions for sexual difficulties.
Journal ArticleDOI

The efficacy of fluoxetine in the treatment of premature ejaculation : A double-blind placebo controlled study

TL;DR: Fluoxetine may be regarded as a safe and effective alternative in the treatment of premature ejaculation and was found to be significantly longer than that in group 2.
Journal ArticleDOI

Clinical follow-up of couples treated for sexual dysfunction

TL;DR: Analysis of data by diagnostic category indicated that sexual desire dysfunction for both men and women was particularly resistant to sustained behavioral change and satisfaction in the marital relationship showed a more varied response pattern.
Journal Article

The role of serotonin in sexual dysfunction: Fluoxetine-associated orgasm dysfunction.

TL;DR: The authors report 6 cases of orgasm dysfunction associated with the use of fluorxetine in 77 depressed outpatients and discusses the possible effects of serotonin on central, spinal, and peripheral anatomical areas in relation to drug-induced sexual dysfunction.
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