Journal ArticleDOI
Efficient palladium-catalyzed coupling of aryl chlorides and tosylates with terminal alkynes: Use of a copper cocatalyst inhibits the reaction
About:
This article is published in Angewandte Chemie.The article was published on 2003-12-15. It has received 345 citations till now. The article focuses on the topics: Palladium & Aryl.read more
Citations
More filters
Journal ArticleDOI
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: Transition-Metal-Free Reactions, Alkynylation of Heterocycles, and Synthesis of Electronic and Electrooptical Molecules: A Review.
Journal ArticleDOI
Transition-metal-catalyzed direct arylation of (hetero)arenes by C-H bond cleavage.
TL;DR: P palladium and ruthenium catalysts have been described that enable the direct arylation of (hetero)arenes with challenging coupling partners--including electrophilic aryl chlorides and tosylates as well as simple arenes in cross-dehydrogenative arylations.
Journal ArticleDOI
Palladium-catalyzed cross-coupling reactions in total synthesis.
TL;DR: In this Review, highlights of a number of selected syntheses are discussed, demonstrating the enormous power of these processes in the art of total synthesis and underscore their future potential in chemical synthesis.
Journal ArticleDOI
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
TL;DR: The application ofadium-catalyzed amination reactions of aryl halides in C-N cross-coupling reactions in the synthesis of heterocycles and pharmaceuticals, in materials science, and in natural product synthesis is discussed.
Journal ArticleDOI
Recent advances in Sonogashira reactions
Rafael Chinchilla,Carmen Nájera +1 more
TL;DR: This critical review focuses on developments in the Sonogashira reaction achieved in recent years concerning catalysts, reaction conditions and substrates.
Related Papers (5)
A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry†
Rafael Chinchilla,Carmen Nájera +1 more
Palladium-based catalytic systems for the synthesis of conjugated enynes by Sonogashira reactions and related alkynylations
Henri Doucet,Jean-Cyrille Hierso +1 more