Journal ArticleDOI
Electrochemical Detection of Uric Acid in Mixed and Clinical Samples: A Review
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In this article, the authors explore the technological advances that have been made in recent years towards the selective analysis of uric acid and critically evaluate how they could be exploited as a basis for a multi analyte sensor incorporating uric acids detection.Abstract:
The present review has sought to explore the technological advances that have been made in recent years towards the selective analysis of uric acid and critically evaluate how they could, in fact, be exploited as a basis for a multi analyte sensor incorporating uric acid detection Numerous strategies have evolved in recent years but these have invariably focused on the manufacture and response characterization of discrete sensors Various methods of obtaining selective detection such as use of uricase enzymes, nanoparticles, carbon nanotubes, polymers, conducting polymers and MIPs are also discussed along with the clinical relevance of UA determinationread more
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Molecular imprinting science and technology: a survey of the literature for the years 2004-2011.
TL;DR: A survey of the literature covering the development of molecular imprinting science and technology over the years 2004–2011 and efforts to apply these polymeric materials to a range of application areas is presented.
Journal ArticleDOI
Simultaneous determination of ascorbic acid, dopamine and uric acid using high-performance screen-printed graphene electrode
TL;DR: Screen-printed graphene electrode (SPGNE) showed excellent electrocatalytic activity for the oxidation of ascorbic acid, dopamine, and uric acid and could be used as a sensitive and selective sensor for simultaneous determination of AA, DA, and UA in biological samples, which may provide a promising alternative in routine sensing applications.
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Advances in enzyme-free electrochemical sensors for hydrogen peroxide, glucose, and uric acid
TL;DR: Enzyme-free (also called nonenzymatic or direct) electrochemical sensors have been widely used for the determination of hydrogen peroxide, glucose, and uric acid as mentioned in this paper.
Journal ArticleDOI
Flexible Organic Electrochemical Transistors for Highly Selective Enzyme Biosensors and Used for Saliva Testing
TL;DR: Flexible organic electrochemical transistors used as high-performance enzyme biosensors, such as uric acid (UA) and cholesterol sensors, are successfully utilized for non-invasive UA detection in human saliva.
Journal ArticleDOI
Simultaneous determination of dopamine and uric acid in the presence of ascorbic acid using Pt nanoparticles supported on reduced graphene oxide
TL;DR: In this article, a Pt/reduced graphene oxide (Pt/RGO) modified glassy carbon electrode was prepared for the detection of dopamine (DA) and uric acid (UA) in the presence of high concentration of ascorbic acid.
References
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Journal ArticleDOI
Nitric Oxide and Peroxynitrite in Health and Disease
TL;DR: Current evidence indicates that most of the cytotoxicity attributed to NO is rather due to peroxynitrite, produced from the diffusion-controlled reaction between NO and another free radical, the superoxide anion, which is presented in detail in this review.
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Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.
TL;DR: It is shown that, at physiological concentrations, urate reduces the oxo-heme oxidant formed by peroxide reaction with hemoglobin, protects erythrocyte ghosts against lipid peroxidation, and protects ERYthrocytes from peroxidative damage leading to lysis.
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Synthesis of New, Nanoporous Carbon with Hexagonally Ordered Mesostructure
Shinae Jun,Sang Hoon Joo,Ryong Ryoo,Michal Kruk,Mietek Jaroniec,Zheng Liu,Tetsu Ohsuna,Osamu Terasaki +7 more
TL;DR: O.R.T. and Z.L.K. as discussed by the authors acknowledge donors of the Petroleum Research Fund administered by the American Chemical Society (ACS), and thank CREST, JST for supports.
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Molecular Imprinting in Cross‐Linked Materials with the Aid of Molecular Templates— A Way towards Artificial Antibodies
TL;DR: In this article, the authors present a method analogous to a mechanism of antibody formation proposed earlier, by which in the presence of interacting monomers a cross-linked polymer is formed around a molecule that acts as a template.
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Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease
Richard J. Johnson,Duk Hee Kang,Daniel I. Feig,Salah D. Kivlighn,John Kanellis,Susumu Watanabe,Katherine R. Tuttle,Bernardo Rodriguez-Iturbe,Jaime Herrera-Acosta,Marilda Mazzali +9 more
TL;DR: It is time to reevaluate the role of uric acid as a risk factor for cardiovascular disease and hypertension and to design human studies to address this controversy.