Elevated hepatic lipase activity and low levels of high density lipoprotein in a normotriglyceridemic, nonobese Turkish population.
Thomas P. Bersot,Gloria Lena Vega,Scott M. Grundy,K.E. Palaoglu,Pamir Atagündüz,Sinan Özbayrakçı,O Gökdemir,Robert W. Mahley +7 more
TLDR
Investigating the cause of low HDL-C levels in Turks found the elevation most likely has a genetic basis, as no dietary or behavioral factors have been identified in the Turkish population that account for increased hepatic triglyceride lipase activity.About:
This article is published in Journal of Lipid Research.The article was published on 1999-03-01 and is currently open access. It has received 86 citations till now. The article focuses on the topics: Turkish population & Hypertriglyceridemia.read more
Citations
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Journal ArticleDOI
Risk factors and cardiovascular disease in Turkey
TL;DR: Since several adverse factors exhibit a rising trend, primary and secondary prevention of cardiovascular disease must assume a much higher priority in various issues in Turkey than it currently does.
Journal ArticleDOI
Reference intervals: current status, recent developments and future considerations.
TL;DR: The aim of the review is to present the current theory and practice of RIs, with special emphasis given to multicenter RIs studies, R is studies for pediatric and geriatric age groups, clinical decision limits and partitioning by genetic effects on RIs.
Journal ArticleDOI
Apolipoprotein C-III, a strong discriminant of coronary risk in men and a determinant of the metabolic syndrome in both genders.
Altan Onat,Gülay Hergenç,Vedat Sansoy,Manfred Fobker,Köksal Ceyhan,Sadık Toprak,Gerd Assmann +6 more
TL;DR: In a population among whom the metabolic syndrome prevails, total- and nonHDL apoC-III are each a determinant in both genders of the metabolic Syndrome and of hypertriglyceridemic hyperapo B, a powerful significant marker of prevalent CHD in men independent of LDL- and HDL-C levels.
Journal ArticleDOI
Normal triglyceride levels despite insulin resistance in African Americans: role of lipoprotein lipase.
Anne E. Sumner,Gloria Lena Vega,David J. Genovese,Karl B. Finley,Richard N. Bergman,Raymond C. Boston +5 more
TL;DR: In African Americans, increased PH-LPL activity is associated with a decrease in TG levels, and the lack of an effect of insulin resistance on PH- LPL could allow LPL to clear TG even in the presence of insulin Resistance.
Journal ArticleDOI
Metabolic syndrome in Turkish children and adolescents
TL;DR: Component of metabolic syndrome such as high blood pressure and high TG, and low HDL-C levels were common among Turkish children and adolescents and strategies should focus on early detection and treatment of these risk variables in Turkish children.
References
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Journal ArticleDOI
Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
TL;DR: A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
Journal ArticleDOI
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
Journal ArticleDOI
High density lipoprotein as a protective factor against coronary heart disease: The Framingham study
TL;DR: The major potent lipid risk factor was HDL cholesterol, which had an inverse association with the incidence of coronary heart disease in either men or women and these associations were equally significant even when other lipids and other standard risk factors for coronaryHeart disease were taken into consideration.
Journal ArticleDOI
Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians.
TL;DR: The results confirm the existence of an insulin resistance syndrome, prevalent in South Asian populations and associated with a pronounced tendency to central obesity in this group, and control of obesity and greater physical activity offer the best chances for prevention of diabetes and CHD.
Journal ArticleDOI
Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials.
R P Mensink,M B Katan +1 more
TL;DR: All fatty acids elevated HDL cholesterol when substituted for carbohydrates, but the effect diminished with increasing unsaturation of the fatty acids, and that for monounsaturates was not.
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