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Open AccessJournal ArticleDOI

Escherichia coli YqhD Exhibits Aldehyde Reductase Activity and Protects from the Harmful Effect of Lipid Peroxidation-derived Aldehydes

TLDR
Results indicate that this enzyme may have a physiological function by protecting the cell against the toxic effect of aldehydes derived from lipid oxidation, and speculate that in Escherichia coli YqhD is part of a glutathione-independent, NADPH-dependent response mechanism to lipid peroxidation.
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This article is published in Journal of Biological Chemistry.The article was published on 2008-03-21 and is currently open access. It has received 210 citations till now. The article focuses on the topics: Lipid peroxidation & Lipid oxidation.

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Nonthermal Dielectric-Barrier Discharge Plasma-Induced Inactivation Involves Oxidative DNA Damage and Membrane Lipid Peroxidation in Escherichia coli

TL;DR: It is demonstrated that FE-DBD plasma-mediated inactivation involves membrane lipid peroxidation in E. coli, and ROS scavengers, such as α-tocopherol (vitamin E), were able to significantly inhibit the extent of lipidperoxidation and oxidative DNA damage.
Journal ArticleDOI

ATP drives direct photosynthetic production of 1-butanol in cyanobacteria

TL;DR: It is shown that artificially engineered ATP consumption through a pathway modification can drive this reaction forward and enables for the first time the direct photosynthetic production of 1-butanol from cyanobacteria Synechococcus elongatus PCC 7942.
Journal ArticleDOI

Cellulosic hydrolysate toxicity and tolerance mechanisms in Escherichia coli.

TL;DR: In this paper, a review of toxicity and tolerance of organic acids, furan derivatives, and phenolic compounds with a specific focus on the important industrial organism Escherichia coli is presented.
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Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes

TL;DR: Compared the effect of various alcohol dehydrogenases (ADH) for the last step of the isobutanol production, E. coli has the yqhD gene which encodes a broad-range ADH and shows better production than ADH2, a result confirmed by activity measurements with isobutyraldehyde.
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Tellurite: history, oxidative stress, and molecular mechanisms of resistance.

TL;DR: This review traces the history of Te in its biological interactions, its enigmatic toxicity, importance in cellular oxidative stress, and interaction in cysteine metabolism.
References
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Book

Free radicals in biology and medicine

TL;DR: 1. Oxygen is a toxic gas - an introduction to oxygen toxicity and reactive species, and the chemistry of free radicals and related 'reactive species'
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

TL;DR: A simple and highly efficient method to disrupt chromosomal genes in Escherichia coli in which PCR primers provide the homology to the targeted gene(s), which should be widely useful, especially in genome analysis of E. coli and other bacteria.
Journal ArticleDOI

Superoxide Radical and Superoxide Dismutases

TL;DR: O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH..
Book

Laboratory techniques in biochemistry and molecular biology

T. S. Work, +1 more
TL;DR: This book discusses laboratory techniques in biochemistry and molecular biology, as well as some of the applications of these techniques in medicine and food science.
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Pathways of Oxidative Damage

TL;DR: This review attempts to present the still-incomplete understanding of how reactive oxygen species are formed inside cells and the mechanisms by which they damage specific target molecules.
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