Journal ArticleDOI
Eu/Tb codoped spindle-shaped fluorinated hydroxyapatite nanoparticles for dual-color cell imaging.
Baojin Ma,Shan Zhang,Jichuan Qiu,Jianhua Li,Yuanhua Sang,Haibing Xia,Huaidong Jiang,Jerome P. Claverie,Hong Liu +8 more
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TLDR
This work has successfully prepared spindle-shaped Eu/Tb codoped FAp nanoparticles by a hydrothermal method and observed that the nanoparticles are cytocompatible even at a concentration as high as 800 μg ml(-1).Abstract:
Lanthanide doped fluorinated hydroxyapatite (FAp) nanoparticles are promising cell imaging nanomaterials but they are excited at wavelengths which do not match the light sources usually found in a commercial confocal laser scanning microscope (CLSM). In this work, we have successfully prepared spindle-shaped Eu/Tb codoped FAp nanoparticles by a hydrothermal method. Compared with single Eu doped FAp, Eu/Tb codoped FAp can be excited by a 488 nm laser, and exhibit both green and red light emission. By changing the amounts of Eu and Tb peaks, the emission in the green region (500–580 nm) can be decreased to the benefit of the emission in the red region (580–720 nm), thus reaching a balanced dual color emission. Using MC3T3-E1 cells co-cultured with Eu/Tb codoped FAp nanoparticles, it is observed that the nanoparticles are cytocompatible even at a concentration as high as 800 μg ml−1. The Eu/Tb codoped FAp nanoparticles are located in the cytoplasm and can be monitored by dual color—green and red imaging with a single excitation light at 488 nm. At a concentration of 200 μg ml−1, the cytoplasm is saturated in 8 hours, and Eu/Tb codoped FAp nanoparticles retain their fluorescence for at least 3 days. The cytocompatible Eu/Tb codoped FAp nanoparticles with unique dual color emission will be of great use for cell and tissue imaging.read more
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Calcium-based biomaterials for diagnosis, treatment, and theranostics
TL;DR: This review focuses on the state-of-the-art progress in CaXs biomaterials, which covers from their categories, characteristics and preparation methods to their bioapplications including diagnosis, treatment, and theranostics.
Journal ArticleDOI
Hydroxyapatite nanobelt/polylactic acid Janus membrane with osteoinduction/barrier dual functions for precise bone defect repair.
Baojin Ma,Jing Han,Shan Zhang,Feng Liu,Shicai Wang,Jiazhi Duan,Yuanhua Sang,Huaidong Jiang,Dong Li,Shaohua Ge,Jinghua Yu,Hong Liu,Hong Liu +12 more
TL;DR: Mandible repair experiments in vivo have shown that the HAp/PLA Janus membrane can promote rat mandible repair on theHAp side and can successfully prevent postoperative adhesion on the PLA side at the same time, which means the HA/PLA membrane with its osteoinduction/barrier dual functions can be applied to repair bone defect precisely.
Journal ArticleDOI
Electromagnetic induction derived micro-electric potential in metal-semiconductor core-shell hybrid nanostructure enhancing charge separation for high performance photocatalysis
Wenqiang Gao,Qilu Liu,Shan Zhang,Yuying Yang,Xiaofei Zhang,Hang Zhao,Wei Qin,Weijia Zhou,Xiaoning Wang,Hong Liu,Hong Liu,Yuanhua Sang +11 more
TL;DR: In this paper, the electromagnetic induction derived micro-electric potential in metal-semiconductor core-shell hybrid nanostructure was used to enhance charge separation in the shell semiconductor photocatalysts.
Journal ArticleDOI
One-Dimensional Hydroxyapatite Nanostructures with Tunable Length for Efficient Stem Cell Differentiation Regulation
Baojin Ma,Shan Zhang,Feng Liu,Jiazhi Duan,Shicai Wang,Jing Han,Yuanhua Sang,Xiaoqiang Yu,Dong Li,Wei Tang,Shaohua Ge,Hong Liu +11 more
TL;DR: Hydroxyapatite nanostructure mediated stem cell osteogenic differentiation excluding growth factors provides a powerful cue to design biomaterials with special nanostructures, and helps to elucidate the interaction of stem cell and biomaterialS nanoststructures.
Journal ArticleDOI
Prolonged fluorescence lifetime of carbon quantum dots by combining with hydroxyapatite nanorods for bio-applications
Baojin Ma,Shan Zhang,Ruoyu Liu,Jichuan Qiu,Lili Zhao,Shicai Wang,Jianhua Li,Yuanhua Sang,Huaidong Jiang,Hong Liu +9 more
TL;DR: The hydrophilic CQD-HAp hybrid nanorods have prolonged fluorescence life, and exhibit a higher fluorescence quantum yield than pure CQDs, and can more efficiently kill human cervical cancer cells, rather than human prostatic cancer cells.
References
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