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Journal ArticleDOI

Evaluation of the properties of a tissue conditioner containing origanum oil as an antifungal additive.

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TLDR
Within the limitations of this in vitro study, origanum oil can be used as an additive to tissue conditioner to reduce the adherence of Candida albicans without significantly affecting its bond strength to heat-polymerized acrylic resin.
Abstract
Statement of problem Adherence and colonization of Candida albicans on tissue conditioners is common and results in irritation of the denture-bearing mucosa. Purpose The purpose of this study was to investigate the antifungal activity and properties of a tissue conditioner by incorporating origanum oil. Material and methods Origanum oil at varying concentrations was incorporated into a poly(methyl methacrylate) based tissue conditioner (Visco-gel), and its antifungal activity against Candida albicans was evaluated at 1 day and 1 week by using the agar punch well method. The adherence of Candida albicans , surface roughness, tensile strength, and bond strength of the tissue conditioner with an optimized origanum oil concentration were evaluated. The data were subjected to 2-way ANOVA (α=.05). Results Sixty vol% origanum oil in tissue conditioner (Visco-gel) showed a mean inhibitory zone of 21.00 ±1.58 mm at 1 day and 13.44 ±0.88 mm at 1 week. The control group showed 90 ±6.80 yeast cells/mm 2 at 1 day and 165 ±7.63 yeast cells/mm 2 at 1 week, whereas the group with origanum oil showed 16 ±1.15 yeast cells/mm 2 at 1 day and 32 ±4.00 yeast cells/mm 2 at 1 week. Surface roughness was less with the incorporation of origanum oil. Tensile strength at 1 day was 0.91 ±0.52 N for the control group, whereas the group with origanum oil showed 0.16 ±0.05 N. At 1 day, the bond strength of 3.97 ±0.75 MPa was observed with control specimens, whereas tissue conditioner with origanum oil showed a bond strength of 3.73 ±0.65 MPa. Conclusions Within the limitations of this in vitro study, origanum oil can be used as an additive to tissue conditioner to reduce the adherence of Candida albicans without significantly affecting its bond strength to heat-polymerized acrylic resin

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Citations
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Role of antifungal medicaments added to tissue conditioners: A systematic review

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The effects of silane-SiO2 nanocomposite films on Candida albicans adhesion and the surface and physical properties of acrylic resin denture base material

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References
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Journal ArticleDOI

Retention of Candida albicans on acrylic resin and silicone of different surface topography.

TL;DR: The resultant surface roughness may facilitate microbial retention and infection and should therefore be kept to a minimum.
Journal ArticleDOI

Susceptibility of methicillin-resistant staphylococci to oregano essential oil, carvacrol and thymol

TL;DR: The results clearly demonstrated that the comparison between the susceptibility of MSS and MRS to oregano oil, carvacrol and thymol showed no significant differences (Fisher's exact test, P > 0.05).
Journal ArticleDOI

Candida-associated denture stomatitis.

TL;DR: A correct oral hygiene is important for the control of the bacterial biofilm present on the denture and on the oral mucosa and it is the fundamental base for the prophylaxis and the therapy of the Candida-associated denture stomatitis.
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Prosthodontic treatment for edentulous patients : complete dentures and implant-supported prostheses

TL;DR: This chapter discusses the Edentulous State, treatment options, and speech Considerations with Complete Dentures as well as clinical Protocols Specific to Implant-Retained and Implanted Supported Prosthodontic Management.
Journal ArticleDOI

Antifungal activities of origanum oil against Candida albicans

TL;DR: The results from this study encourage examination of the efficacy of origanum oil in other forms of systemic and superficial fungal infections and exploration of its broad spectrum effect against other pathogenic manifestations including malignancy.
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