Evidence and Implications of Inhomogeneity in Tectorial Membrane Elasticity
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TLDR
This work subdivide the tectorial membrane into three longitudinal regions and five radial zones and map the shear modulus of the TM using atomic force microscopy, and presents evidence that the TM elasticity varies radially, after the distribution of type A collagen fibrils.About:
This article is published in Biophysical Journal.The article was published on 2004-10-01 and is currently open access. It has received 69 citations till now. The article focuses on the topics: Tectorial membrane & Hair cell.read more
Citations
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Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells ‘feel’ outside and in?
TL;DR: Continuity of deformation from the matrix into the cell and further into the cytoskeleton-caged and -linked nucleus also supports the existence of mechanisms that direct processes such as gene expression in the differentiation of stem cells.
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Self-assembled peptide nanotubes are uniquely rigid bioinspired supramolecular structures.
TL;DR: This work finds that the averaged point stiffness of the nanotubes is 160 N/m, and that they have a correspondingly high Young's modulus of approximately 19 GPa, as calculated by finite element analysis.
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Probing mechanical properties of living cells by atomic force microscopy with blunted pyramidal cantilever tips.
TL;DR: A contact model of a blunted pyramidal tip indenting an elastic half-space is developed and the suitability of pyramides tips for probing mechanical properties of soft gels and living cells is assessed.
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Atomic force microscopy detects differences in the surface brush of normal and cancerous cells.
Swaminathan Iyer,Ravi Gaikwad,Venkatesh Subba-Rao,Venkatesh Subba-Rao,Craig D. Woodworth,Igor M. Sokolov +5 more
TL;DR: It is found that normal cells have brushes of one length, whereas cancerous cells have mostly two brush lengths of significantly different densities, which suggest that brush layers should be taken into account when characterizing the cell surface by mechanical means.
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The Physiology of Mechanoelectrical Transduction Channels in Hearing
TL;DR: This approach has shown that small (1-100 nm) deflections of the hair-cell stereociliary bundle are transmitted via interciliary tip links to open MT channels at the tops of the stereocilia, which controls transducer fast adaptation and force generation by the hair bundle.
References
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Book
Theory of elasticity
TL;DR: The theory of the slipline field is used in this article to solve the problem of stable and non-stressed problems in plane strains in a plane-strain scenario.
Book
Theory of elasticity
TL;DR: The equilibrium of rods and plates Elastic waves Dislocations Thermal conduction and viscosity in solids Mechanics of liquid crystals Index as discussed by the authors The equilibrium of rod and plate elastic waves Elastic waves
Book
Advanced mathematical methods for scientists and engineers
Carl M. Bender,Steven A. Orszag +1 more
TL;DR: A self-contained presentation of the methods of asymptotics and perturbation theory, methods useful for obtaining approximate analytical solutions to differential and difference equations is given in this paper.
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Procedures for Detecting Outlying Observations in Samples
TL;DR: In this paper, a procedure for determining statistically whether the highest observation, lowest observation, highest and lowest observations, or more of the observations in the sample are statistical outliers is given.