Journal ArticleDOI
Fabrication of nanopatterned PLGA films of curcumin and TPGS for skin cancer.
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TLDR
Poly(lactic-co-glycolic acid) nanopatterned films (NPFs) showed good in vitro cytotoxicity towards human skin cancer cell line (A431) when compared to that of unpattern films and could be used as an alternate treatment for skin cancer.About:
This article is published in International Journal of Pharmaceutics.The article was published on 2020-03-30. It has received 11 citations till now. The article focuses on the topics: PLGA.read more
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The use of TPGS in drug delivery systems to overcome biological barriers
Marcela Tavares Luiz,Leonardo Delello Di Filippo,Renata Carolina Alves,Victor Hugo Sousa Araujo,Jonatas Lobato Duarte,Juliana Maldonado Marchetti,Marlus Chorilli +6 more
TL;DR: D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) is a biocompatible macromolecule that has been evaluated as a permeation enhancer and its most recent application in nanomedicine field to overcome biological barriers is addressed.
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A comprehensive review on natural bioactive films with controlled release characteristics and their applications in foods and pharmaceuticals
TL;DR: In this paper, the role of film forming matrices, loading of active agents into biopolymeric nanocarriers, the factors affecting the controlled release properties of active films as well as their underlying mechanisms are reviewed.
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A comprehensive review of the therapeutic potential of curcumin nanoformulations.
TL;DR: A literature review on herbal medicine and commercial products in the global market showed that curcumin (Cur) has many therapeutic benefits compared to other natural ingredients as mentioned in this paper. But despite the unique properties of Cur, its use in clinical trials is very limited.
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Combination of nano-hydroxyapatite and curcumin in a biopolymer blend matrix: Characteristics and drug release performance of fibrous composite material systems
TL;DR: The findings obtained from this research are expected to contribute to the appropriate design of nanofiber-based composite materials not only for drug delivery systems but also for the fabrication of biomaterials toward different biomedical applications.
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Progress in the drug encapsulation of poly(lactic-co-glycolic acid) and folate-decorated poly(ethylene glycol)-poly(lactic-co-glycolic acid) conjugates for selective cancer treatment.
TL;DR: A deeper understanding of the constituents and interactions of PLGA-conjugated materials to ensure successful conjugation in PLGA material design and the subsequent biomedical applications is provided.
References
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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V.
TL;DR: The Annexin V assay offers the possibility of detecting early phases of apoptosis before the loss of cell membrane integrity and permits measurements of the kinetics of apoptotic death in relation to the cell cycle.
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New approaches to nanofabrication: molding, printing, and other techniques.
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Nanosize and Vitality: TiO2 Nanotube Diameter Directs Cell Fate
TL;DR: Self-assembled layers of vertically oriented TiO2 nanotubes with defined diameters between 15 and 100 nm are generated and show that adhesion, spreading, growth, and differentiation of mesenchymal stem cells are critically dependent on the tube diameter.
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Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics
TL;DR: Select enhanced osteoblast adhesion was independent of surface chemistry and material phase but was dependent on the surface topography (specifically on grain and pore size) of nanophase ceramics.