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Field flow fractionation techniques to explore the “nano-world”
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This review considers FFF applications in the food, biomedical, and environmental sectors, mostly drawn from the past 4 y, and underlines the prominent role of asymmetrical flow FFF within the FFF family.Abstract:
Field flow fractionation (FFF) techniques are used to successfully characterize several nanomaterials by sizing nano-entities and producing information about the aggregation/agglomeration state of nanoparticles. By coupling FFF techniques to specific detectors, researchers can determine particle-size distributions (PSDs), expressed as mass-based or number-based PSDs. This review considers FFF applications in the food, biomedical, and environmental sectors, mostly drawn from the past 4 y. It thus underlines the prominent role of asymmetrical flow FFF within the FFF family. By concisely comparing FFF techniques with other techniques suitable for sizing nano-objects, the advantages and the disadvantages of these instruments become clear. A consideration of select recent publications illustrates the state of the art of some lesser-known FFF techniques and innovative instrumental set-ups.read more
Citations
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Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity
TL;DR: A multi‐step approach of incremental complexity to measure particle size distribution and size stability of NEPs, consisting of a quick preliminary step to assess sample integrity and stability by low resolution techniques (pre‐screening), followed by the combination of complementary high resolution sizing measurements performed both in simple buffers and in complex biological media.
Journal ArticleDOI
Separation, characterization and identification of microplastics and nanoplastics in the environment.
TL;DR: This critical review elaborates the principles and applications of diverse analytical instruments or techniques for separation, characterization and quantification of MPs in the environment and highlights emerging and promising characterization techniques that may have been overlooked by research communities to study MPs.
Journal ArticleDOI
Are existing standard methods suitable for the evaluation of nanomedicines: some case studies.
Sabrina Gioria,Fanny Caputo,Patricia Urbán,Ciaran Manus Maguire,Susanne Bremer-Hoffmann,Adriele Prina-Mello,Luigi Calzolai,Dora Mehn +7 more
TL;DR: This work illustrates the shortcomings of currently used standardized methods when applied to medical-nanoparticles to assess particle size, drug loading, drug release and in vitro safety, and addresses some identified needs.
Journal ArticleDOI
Nanoplastic Analysis by Online Coupling of Raman Microscopy and Field-Flow Fractionation Enabled by Optical Tweezers.
Christian Schwaferts,Vanessa Sogne,Roland Welz,Florian Meier,Thorsten Klein,Reinhard Niessner,Martin Elsner,Natalia P. Ivleva +7 more
TL;DR: The hyphenation of particle separation / characterization with subsequent chemical identification by on-line Raman microspectroscopy is realized with potential for application in nanoplastic analysis, as well as many other fields of nanomaterials.
Journal ArticleDOI
Atomic spectrometry update. Review of advances in the analysis of metals, chemicals and materials
TL;DR: A review of recent developments in applications of atomic spectrometry to the characterisation of metals, chemicals and materials can be found in this paper, where the authors identify research trends solely from an annual review of the literature and a certain perspective can be obtained from examining the developments described in recent years in this ASU review series.
References
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Book
Absorption and Scattering of Light by Small Particles
TL;DR: In this paper, a Potpourri of Particles is used to describe surface modes in small Particles and the Angular Dependence of Scattering is shown to be a function of the size of the particles.
BookDOI
There's plenty of room at the bottom
TL;DR: The theory of chemical processes is based on theoretical physics as mentioned in this paper, and physics supplies the foundation of chemistry, and the biological example of writing information on a small scale has inspired to think of something that should be possible.
Journal ArticleDOI
Quantum Dots and Their Multimodal Applications: A Review
TL;DR: In this paper, the decoupling of quantum effects on excitation and emission is described, along with the use of quantum dots as sensitizers in phosphors, and the multimodal applications of quantum dot, including in electroluminescence device, solar cell and biological imaging.
Journal ArticleDOI
There’s plenty of room at the bottom
TL;DR: The theory of chemical processes is based on theoretical physics as mentioned in this paper, and physics supplies the foundation of chemistry, and the biological example of writing information on a small scale has inspired to think of something that should be possible.
Journal ArticleDOI
Biological applications of quantum dots
Timothy Jamieson,Raheleh Bakhshi,Daniela Petrova,Rachael Pocock,Mo Imani,Alexander M. Seifalian,Alexander M. Seifalian +6 more
TL;DR: Quantum dots (QDs) are a class of inorganic fluorophore which are rapidly being applied to existing and emerging technologies, and could have an important role in many areas Significant challenges remain, which must be understood and more fully defined before they can be widely validated.