Journal ArticleDOI
Following in the Footsteps of the North Karelia Project: Prevention of Type 2 Diabetes.
TLDR
The practical implementation of screening of individuals for high type 2 diabetes risk and prevention of type 2abetes in Finland at the population level is discussed and how they have contributed to European level initiatives is described.Abstract:
The prevalence as well as actual number of people with type 2 diabetes has been increasing in Finland during the past decades, in parallel with an increase in overweight and obesity. Besides obesity, population aging is among the main drivers of increasing numbers of diabetic patients. Type 2 diabetes brings along complications, most importantly cardiovascular diseases, and increasing type 2 diabetes prevalence has also been suggested to lead to a new upward turn in cardiovascular diseases. Therefore, it is important to implement activities to prevent type 2 diabetes. We present the trial evidence for the prevention of type 2 diabetes with emphasis on the Finnish Diabetes Prevention Study findings. Furthermore, we discuss the practical implementation of screening of individuals for high type 2 diabetes risk and prevention of type 2 diabetes in Finland at the population level and describe how they have contributed to European level initiatives.read more
Citations
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Nutrient intake and dietary changes during a 2-year multi-domain lifestyle intervention among older adults: secondary analysis of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) randomised controlled trial.
Jenni Lehtisalo,Tiia Ngandu,Paivi Valve,Riitta Antikainen,Tiina Laatikainen,Timo E. Strandberg,Hilkka Soininen,Jaakko Tuomilehto,Miia Kivipelto,Jaana Lindström +9 more
TL;DR: In this article, a randomized 2-year multi-domain lifestyle intervention trial aiming at prevention of cognitive decline among 631 participants in the intervention and 629 in the control group, aged 60-77 years at baseline.
Journal ArticleDOI
A Roadmap on the Prevention of Cardiovascular Disease Among People Living With Diabetes
Sharon Mitchell,Belma Malanda,Albertino Damasceno,Robert H. Eckel,Dan Gaita,Kornelia Kotseva,James L. Januzzi,George A. Mensah,Jorge Plutzky,Maksym Prystupiuk,Lars Rydén,Jorge Thierer,Salim S. Virani,Laurence S. Sperling +13 more
TL;DR: The ideal pathway of care for those living with type 2 diabetes to prevent and manage CVD is a key feature of this consensus document, and the roadblocks and potential solutions to patient care are offered based on key stages of the patient care pathway.
Changes in lifestyle modestly reduce the estimated cardiovascular disease risk in one-year follow-up of the Finnish diabetes prevention program (FIN-D2D)
Nina Rautio,Jari Jokelainen,Auli Polonen,Heikki Oksa,Markku Peltonen,Mauno Vanhala,Hannu Puolijoki,Leena Moilanen,Jaakko Tuomilehto,Matti Uusitupa,Sirkka Keinänen-Kiukaanniemi,Sirkka Keinänen-Kiukaanniemi,Timo Saaristo +12 more
TL;DR: In this paper, the authors assessed whether changes in self-rated physical activity and diet during a type 2 diabetes prevention program were associated with changes in estimated 10-year risk for cardiovascular disease (CVD) events and mortality in people at high risk for T2D.
Journal ArticleDOI
International Society for the Study of Fatty Acids and Lipids 2016 Debate: For Science-Based Dietary Guidelines on Fats, Meta-Analysis and Systematic Reviews Are Decisive
TL;DR: It is concluded that nutritional guidelines on fat need a proper scientific basis in which randomized controlled trials (RCTs) with clinical endpoints and their meta-analyses are essential and decisive.
Journal ArticleDOI
Effectiveness of a web-based real-life weight management program: Study design, methods, and participants' baseline characteristics
TL;DR: Insight is brought into how internet-based technologies can be implemented in the virtual management of obesity by presenting the design, methods and participants’ baseline characteristics in a real-lifeinternet-based weight management program.
References
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Journal ArticleDOI
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C. Knowler,Elizabeth Barrett-Connor,Sarah E. Fowler,Richard F. Hamman,John M. Lachin,Elizabeth A. Walker,David M. Nathan +6 more
TL;DR: In this paper, the authors compared a lifestyle intervention with metformin to prevent or delay the development of Type 2 diabetes in nondiabetic individuals. And they found that the lifestyle intervention was significantly more effective than the medication.
Journal ArticleDOI
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.
Jaakko Tuomilehto,Jon Lindstrom,Johan G. Eriksson,Valle Tt,Helena Hämäläinen,Pirjo Ilanne-Parikka,Keinänen-Kiukaanniemi S,Mauri Laakso,Anne Louheranta,Rastas M,Salminen,Matti Uusitupa +11 more
TL;DR: Type 2 diabetes can be prevented by changes in the lifestyles of high-risk subjects by means of individualized counseling aimed at reducing weight, total intake of fat, and intake of saturated fat and increasing intake of fiber and physical activity.
Journal ArticleDOI
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
Tiia Ngandu,Tiia Ngandu,Jenni Lehtisalo,Alina Solomon,Alina Solomon,Esko Levälahti,Satu Ahtiluoto,Riitta Antikainen,Lars Bäckman,Tuomo Hänninen,Antti Jula,Tiina Laatikainen,Tiina Laatikainen,Jaana Lindström,Francesca Mangialasche,Teemu Paajanen,Satu Pajala,Markku Peltonen,Rainer Rauramaa,Anna Stigsdotter-Neely,Timo E. Strandberg,Timo E. Strandberg,Jaakko Tuomilehto,Hilkka Soininen,Miia Kivipelto +24 more
TL;DR: In the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER), a proof-of-concept randomised controlled trial, the authors aimed to assess a multidomain approach to prevent cognitive decline in at-risk elderly people from the general population.
Journal ArticleDOI
The Finnish Diabetes Prevention Study (DPS) Lifestyle intervention and 3-year results on diet and physical activity
Jaana Lindström,Anne Louheranta,Marjo Mannelin,Rastas M,Virpi Salminen,Johan G. Eriksson,Matti Uusitupa,Jaakko Tuomilehto +7 more
TL;DR: The intensive lifestyle intervention produced long-term beneficial changes in diet, physical activity, and clinical and biochemical parameters and reduced diabetes risk.