Formate cross-feeding and cooperative metabolic interactions revealed by transcriptomics in co-cultures of acetogenic and amylolytic human colonic bacteria.
Jenny Angelica Laverde Gomez,Indrani Mukhopadhya,Sylvia H. Duncan,Petra Louis,Sophie Shaw,Elaina Susan Renata Collie-Duguid,Emmanuelle H. Crost,Nathalie Juge,Harry J. Flint +8 more
TLDR
Cross‐feeding between formate‐producing species and acetogens may be a significant factor in short chain fatty acid formation in the colon contributing to high rates of acetate production.Abstract:
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The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics
Kelly S. Swanson,Glenn R. Gibson,Robert W. Hutkins,Raylene A. Reimer,Gregor Reid,Kristin Verbeke,Karen P. Scott,Hannah D. Holscher,Meghan B. Azad,Nathalie M. Delzenne,Mary Ellen Sanders +10 more
TL;DR: This Consensus Statement outlines the definition and scope of the term ‘synbiotics’ as determined by an expert panel convened by the International Scientific Association for Probiotics and Prebiotics in May 2019 and explores the levels of evidence, safety, effects upon targets and implications for stakeholders of the synbiotic concept.
Journal ArticleDOI
Blautia-a new functional genus with potential probiotic properties?
Xuemei Liu,Mao Bingyong,Jiayu Gu,Jiaying Wu,Cui Shumao,Wang Gang,Jianxin Zhao,Hao Zhang,Wei Chen +8 more
TL;DR: Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the feces and intestines of mammals as discussed by the authors based on phenotypic and phylogenetic analyses.
Journal ArticleDOI
The rumen microbiome: balancing food security and environmental impacts.
TL;DR: In this paper, the authors describe the composition, ecology and metabolism of the rumen microbiome, and the impact on host physiology and the environment, and discuss the most pertinent methane mitigation strategies that emerged to balance food security and environmental impacts.
Journal ArticleDOI
Advancing human gut microbiota research by considering gut transit time
Nicola Procházková,Gwen Falony,Lars O. Dragsted,Tine Rask Licht,Jeroen Raes,Henrik Munch Roager +5 more
TL;DR: It is argued that by taking into account the interindividual and intraindividual differences in gut transit time, the understanding of diet–microbiota interactions and disease-related microbiome signatures can be advanced, since these may often be confounded by transient or persistent alterations in transit time.
References
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Colorimetric Method for Determination of Sugars and Related Substances
TL;DR: In this article, a method was developed to determine submicro amounts of sugars and related substances using a phenol-sulfuric acid reaction, which is useful for the determination of the composition of polysaccharides and their methyl derivatives.
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HTSeq—a Python framework to work with high-throughput sequencing data
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Differential expression analysis for sequence count data.
Simon Anders,Wolfgang Huber +1 more
TL;DR: A method based on the negative binomial distribution, with variance and mean linked by local regression, is proposed and an implementation, DESeq, as an R/Bioconductor package is presented.
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TopHat: discovering splice junctions with RNA-Seq
TL;DR: The TopHat pipeline is much faster than previous systems, mapping nearly 2.2 million reads per CPU hour, which is sufficient to process an entire RNA-Seq experiment in less than a day on a standard desktop computer.
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Prokaryotes: The unseen majority
TL;DR: The number of prokaryotes and the total amount of their cellular carbon on earth are estimated to be 4-6 x 10(30) cells and 350-550 Pg of C (1 Pg = 10(15) g), respectively, which is 60-100% of the estimated total carbon in plants.