Open Access
From Basic Science to Clinical Applications
Timothy E. Foster,Brian L. Puskas,Bert R. Mandelbaum,Michael B. Gerhardt,Scott A. Rodeo,Santa Monica +5 more
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The article was published on 2009-01-01 and is currently open access. It has received 667 citations till now. The article focuses on the topics: Applied science.read more
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Journal ArticleDOI
Clinical and Magnetic Resonance Imaging Outcomes Following Platelet Rich Plasma Treatment for Elbow Tendinosis
TL;DR: PRP treatment for lateral or medial elbow tendinosis resulted in significant improvements in pain levels, elbow function and sports/recreational activities and suggests that PRP may improve clinical outcomes for up to two years.
Journal ArticleDOI
Platelet Rich Plasma Intra Articular Injection forChronic Synovitis Treatment in Patients withHaemophilia One Year Follow Up
María Eulalia Landro,Carla Daffunchio,Guillermo Cambiaggi,Gustavo Galatro,Pablo Salgado,Egle Honorat,Horacio Caviglia +6 more
TL;DR: This treatment relies on the biological properties of PRP, which contains alpha-granules with growth factors and proteins used in joint homeostasis, healing mechanisms and tissue regeneration, to stimulate healing of the joint and provide symptomatic relief.
Posted ContentDOI
KIT ligand protects against both light-induced and genetic photoreceptor degeneration
Huirong Li,Huirong Li,Lili Lian,Bo Liu,Yu Chen,Yu Chen,Jinglei Yang,Shuhui Jian,Jiajia Zhou,Ying Xu,Xiaoyin Ma,Xiaoyin Ma,Jia Qu,Ling Hou,Ling Hou +14 more
TL;DR: It is shown in mouse models that signaling through the tyrosine kinase receptor KIT protects photoreceptor cells against both light-induced and inherited retinal degeneration.
Journal ArticleDOI
New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance
Tanja Klein-Rodewald,Kateryna Micklich,Adrian Sanz-Moreno,Julia Calzada-Wack,Monica Tost,Thure Adler,Matthias Klaften,Sibylle Sabrautzki,Bernhard Aigner,Markus J. Kraiger,Valerie Gailus-Durner,Helmut Fuchs,Albert Gründer,Heike L. Pahl,Eckhard Wolf,Martin Hrabé de Angelis,Birgit Rathkolb +16 more
TL;DR: In this article , the role of KIT mutations in the context of breast cancer was investigated. But it is still unsatisfactory because of primary or secondary resistance to therapy, which is why it is difficult to find the optimal treatment for KIT-induced cancers.
Journal ArticleDOI
Leukocyte and Platelet-Rich Plasma (L-PRP) in Tendon Models: A Systematic Review and Meta-Analysis of in vivo/in vitro Studies
TL;DR: A systematic review on the application of leukocyte and platelet-rich plasma (L-PRP) in tendon models by reviewing in vivo/in vitro studies was performed as discussed by the authors .
References
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Atherosclerosis — An Inflammatory Disease
TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
Journal Article
Atherosclerosis is an Inflammatory Disease
光宏 横山,Russell Ross +1 more
TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.
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C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women
TL;DR: The addition of the measurement of C-reactive protein to screening based on lipid levels may provide an improved method of identifying persons at risk for cardiovascular events.
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Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial
TL;DR: Dietary supplementation with n-3 PUFA led to a clinically important and statistically significant benefit and vitamin E had no benefit and its effects on fatal cardiovascular events require further exploration.
Journal ArticleDOI
Atherosclerosis: The Road Ahead
TL;DR: Elevated levels of serum cholesterol are probably unique through the hepatic LDL receptor pathway, as evi-in being sufficient to drive the development of athero-denced by the fact that lack of functional LDL receptors sclerosis in humans and experimental animals, even in is responsible for the massive accumulation of LDL in the absence of other known risk factors.