Open Access
From Basic Science to Clinical Applications
Timothy E. Foster,Brian L. Puskas,Bert R. Mandelbaum,Michael B. Gerhardt,Scott A. Rodeo,Santa Monica +5 more
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The article was published on 2009-01-01 and is currently open access. It has received 667 citations till now. The article focuses on the topics: Applied science.read more
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The effects of plasma rich in growth factors (PRGF-Endoret) on healing of medial collateral ligament of the knee
Tomokazu Yoshioka,Akihiro Kanamori,Toshikatsu Washio,Katsuya Aoto,Kenta Uemura,Masataka Sakane,Naoyuki Ochiai +6 more
TL;DR: Findings provide evidence that local administration of PRGF-Endoret promotes early steps in ligament healing and the repair of structural properties in a rabbit model, and would be a useful product in clinical treatment of ligament injuries.
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Current concepts for the use of platelet-rich plasma in the foot and ankle.
TL;DR: Platelet-rich plasma (PRP) injections have been used and studied since the 1970s and has an advantage over many tissue engineering products in that it is autologous.
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Application of Platelet-Rich Plasma to Disorders of the Knee Joint
TL;DR: A comprehensive review of the literature supports the potential use of PRP both nonoperatively and intraoperatively, but highlights the absence of large clinical studies and the lack of standardization between method, product, and clinical efficacy.
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Equine autologous platelet concentrates : A comparative study between different available systems
TL;DR: Haematological and biochemical characteristics varied markedly among 5 techniques used in the field to produce APCs in horses, and these discrepancies could have an impact on clinical outcomes.
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Steroid vs. Platelet-Rich Plasma in Ultrasound-Guided Sacroiliac Joint Injection for Chronic Low Back Pain.
TL;DR: Despite widespread use of steroids to treat sacroiliac joint pain, their duration of pain reduction is short and platelet‐rich plasma (PRP) can potentially enhance tissue healing and may have a longer‐lasting effect on pain.
References
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Atherosclerosis — An Inflammatory Disease
TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
Journal Article
Atherosclerosis is an Inflammatory Disease
光宏 横山,Russell Ross +1 more
TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.
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C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women
TL;DR: The addition of the measurement of C-reactive protein to screening based on lipid levels may provide an improved method of identifying persons at risk for cardiovascular events.
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Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial
TL;DR: Dietary supplementation with n-3 PUFA led to a clinically important and statistically significant benefit and vitamin E had no benefit and its effects on fatal cardiovascular events require further exploration.
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Atherosclerosis: The Road Ahead
TL;DR: Elevated levels of serum cholesterol are probably unique through the hepatic LDL receptor pathway, as evi-in being sufficient to drive the development of athero-denced by the fact that lack of functional LDL receptors sclerosis in humans and experimental animals, even in is responsible for the massive accumulation of LDL in the absence of other known risk factors.