Open Access
From Basic Science to Clinical Applications
Timothy E. Foster,Brian L. Puskas,Bert R. Mandelbaum,Michael B. Gerhardt,Scott A. Rodeo,Santa Monica +5 more
Reads0
Chats0
About:
The article was published on 2009-01-01 and is currently open access. It has received 667 citations till now. The article focuses on the topics: Applied science.read more
Citations
More filters
Journal ArticleDOI
Bone grafts and biomaterials substitutes for bone defect repair: A review.
Wenhao Wang,Kelvin W.K. Yeung +1 more
TL;DR: The currently available bone grafts and bone substitutes as well as the biological and bio-inorganic factors for the treatments of bone defect are reviewed.
Journal ArticleDOI
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
TL;DR: How the development of future treatments for central nervous system (CNS) disorders can take advantage of the intimate and mutual interactions of the gut microbiota with the brain by exploring the role of SCFAs in the regulation of neuro-immunoendocrine function is highlighted.
Journal ArticleDOI
Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors
Paola Romina Amable,Rosana Bizon Vieira Carias,Marcus Vinicius Telles Teixeira,Ítalo da Cruz Pacheco,Ronaldo J F C do Amaral,José Mauro Granjeiro,Radovan Borojevic +6 more
TL;DR: This study resulted in a consistent PRP preparation method that yielded a cytokine and growth factor pool from different donors with high reproducibility and its content characterization will allow us to understand and improve the clinical outcomes.
Journal ArticleDOI
Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis
Giuseppe Filardo,Elizaveta Kon,Roberto Buda,Antonio Timoncini,Alessandro Di Martino,Annarita Cenacchi,Pier Maria Fornasari,Sandro Giannini,Maurilio Marcacci +8 more
TL;DR: These findings indicate that treatment with PRP injections can reduce pain and improve knee function and quality of life with short-term efficacy, and further studies are needed to confirm these results and understand the mechanism of action.
Journal ArticleDOI
Platelet-rich plasma: a milieu of bioactive factors.
TL;DR: It is supported that more than just platelets are playing a role in clinical responses to PRP, and the clinical use can theoretically be matched to the pathology being treated in an effort to improve clinical efficacy.
References
More filters
Journal ArticleDOI
Nonunions treated with autologous preparation rich in growth factors.
Mikel Sánchez,Eduardo Anitua,Ramón Cugat,Juan Azofra,Jorge Guadilla,Roberto Seijas,Isabel Andia +6 more
TL;DR: This study shows that PRGF technology is clinically safe and can enhance the healing of nonhypertrophic nonunions.
Journal ArticleDOI
Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth
Masahiro Nozaki,Yong Li,Yong Li,Jinhong Zhu,Jinhong Zhu,Fabrisia Ambrosio,Fabrisia Ambrosio,Kenji Uehara,Kenji Uehara,Freddie H. Fu,Johnny Huard +10 more
TL;DR: Intramuscular injection of suramin after a contusion injury improved overall skeletal muscle healing and suggests a possible mechanism for the beneficial effects that this pharmacologic agent exhibits in vivo.
Journal ArticleDOI
Lipids and the immune response: from molecular mechanisms to clinical applications
TL;DR: This review critically evaluates recent studies investigating the effects of fatty acids on immune and inflammatory responses in both healthy individuals and in patients with inflammatory diseases, with some reference to animal studies where relevant.
Journal ArticleDOI
Long-term supplementation with n-3 fatty acids, II: Effect on neutrophil and monocyte chemotaxis.
Erik Berg Schmidt,K. Varming,Jens Oluf Pedersen,Lervang Hh,Niels Grunnet,C. Jersild,Jørn Dyerberg +6 more
TL;DR: Findings lend support to a role for n-3 PUFA in the management of chronic inflammatory and atherosclerotic vascular diseases.