Journal ArticleDOI
Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications
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TLDR
This review elucidate FGNs-bioorganism interactions and summarize recent advancements on designing FGN-based two-dimensional and three-dimensional architectures as multifunctional biological platforms.Abstract:
Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely unique physical and chemical properties and physiological ability to interfere and/or interact with bioorganisms; as a result, FGNs present manifold possibilities for diverse biological applications. Beyond their use in drug/gene delivery, phototherapy, and bioimaging, recent studies have revealed that FGNs can significantly promote interfacial biointeractions, in particular, with proteins, mammalian cells/stem cells, and microbials. FGNs can adsorb and concentrate nutrition factors including proteins from physiological media. This accelerates the formation of extracellular matrix, which eventually promotes cell colonization by providing a more beneficial microenvironment for cell adhesion and growth. Furthermore, FGNs can also interact with cocultured cells by physical or chemical stimulation, which significantly mediate their cellular signaling and biological performance. In this review, we elucidate FGNs–bioorganism int...read more
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Synthesis, properties, and applications of graphene oxide/reduced graphene oxide and their nanocomposites
TL;DR: In this paper, the authors review the synthesis techniques most commonly used to produce these graphene derivatives, discuss how synthesis affects their key material properties, and highlight some examples of nanocomposites with unique and impressive properties.
Journal ArticleDOI
Carbon dots: synthesis, formation mechanism, fluorescence origin and sensing applications
TL;DR: Carbon dots have received an increasing amount of attention because of their significant advantages in terms of low toxicity, chemical inertness, tunable fluorescence, good water solubility, and physicochemical properties as mentioned in this paper.
Journal ArticleDOI
Flexible Graphene-Based Wearable Gas and Chemical Sensors
TL;DR: The role of graphene in fabricating flexible gas sensors for the detection of various hazardous gases, including nitrogen dioxide, ammonia, hydrogen, hydrogen sulfide, carbon dioxide, sulfur dioxide, and humidity in wearable technology, is discussed.
Journal ArticleDOI
Promises, facts and challenges for graphene in biomedical applications
Giacomo Reina,Jose M. González-Domínguez,Alejandro Criado,Ester Vázquez,Alberto Bianco,Maurizio Prato +5 more
TL;DR: This Tutorial Review critically describes the latest developments of the graphene family materials into the biomedical field and analyzes graphene-based devices starting from graphene synthetic strategies, functionalization and processibility protocols up to the final in vitro and in vivo applications.
Journal ArticleDOI
A review on graphene-based nanocomposites for electrochemical and fluorescent biosensors
TL;DR: Graphene and its oxygenated derivatives, including reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the field of biosensors as discussed by the authors, and the discovery of graphene has spectacularly accelerated research on fabricating low-cost electrode materials because of its unique physical properties, including high specific surface area, high carrier mobility, high electrical conductivity, flexibility.
References
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Journal ArticleDOI
Detection of microRNA in Tumor Cells using Exonuclease III and Graphene Oxide-Regulated Signal Amplification
TL;DR: A label-free, ultrasensitive graphene oxide (GO)-based probe for the detection of oligonucleotides by laser desorption/ionization mass spectrometry (LDI-MS) and utilized this R6G-GO probe in the Detection of a single-nucleotide polymorphism (SNP) in the Arg249Ser unit of the TP53 gene.
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Synergistic photothermal antimicrobial therapy using graphene oxide/polymer composite layer-by-layer thin films
TL;DR: In this article, an efficient and simple synergistic antimicrobial therapy for lysing pathogenic E. coli K12 MG1655 using layer-by-layer (LbL) films of graphene oxide (GO) and poly(allylamine hydrochloride) (PAH) was reported.
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Electro-stimulated release from a reduced graphene oxide composite hydrogel
Nicky Mac Kenna,Paul Calvert,Aoife Morrin,Gordon G. Wallace,Simon E. Moulton,Simon E. Moulton +5 more
TL;DR: A high level of control and flexibility was achieved demonstrating the applicability of this system for localised drug delivery applications.
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Eighteen-month assessment of 3D graphene oxide aerogel-modified 3D graphite fiber brush electrode as a high-performance microbial fuel cell anode
TL;DR: In this paper, a 3D-3D structured anode composed of graphite fiber brush (GFB) modified with graphene oxide aerogel (GOA) was evaluated during 18-month incubation.
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Electrochemical Detection of a Cancer Biomarker mir‐21 in Cell Lysates Using Graphene Modified Sensors
TL;DR: The proposed electrochemical yes-no system does not require any purification and/or amplifica- tion step prior to fast detection of mir-21 from real sam- ples, and it is capable of analyzing mir- 21 in the cell lysates of Mir-21 positive breast cancer cell line (MCF-7) contrast to mir-20 negative hepatoma cellline (HUH-7).