Journal ArticleDOI
Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications
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TLDR
This review elucidate FGNs-bioorganism interactions and summarize recent advancements on designing FGN-based two-dimensional and three-dimensional architectures as multifunctional biological platforms.Abstract:
Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely unique physical and chemical properties and physiological ability to interfere and/or interact with bioorganisms; as a result, FGNs present manifold possibilities for diverse biological applications. Beyond their use in drug/gene delivery, phototherapy, and bioimaging, recent studies have revealed that FGNs can significantly promote interfacial biointeractions, in particular, with proteins, mammalian cells/stem cells, and microbials. FGNs can adsorb and concentrate nutrition factors including proteins from physiological media. This accelerates the formation of extracellular matrix, which eventually promotes cell colonization by providing a more beneficial microenvironment for cell adhesion and growth. Furthermore, FGNs can also interact with cocultured cells by physical or chemical stimulation, which significantly mediate their cellular signaling and biological performance. In this review, we elucidate FGNs–bioorganism int...read more
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Synthesis, properties, and applications of graphene oxide/reduced graphene oxide and their nanocomposites
TL;DR: In this paper, the authors review the synthesis techniques most commonly used to produce these graphene derivatives, discuss how synthesis affects their key material properties, and highlight some examples of nanocomposites with unique and impressive properties.
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Carbon dots: synthesis, formation mechanism, fluorescence origin and sensing applications
TL;DR: Carbon dots have received an increasing amount of attention because of their significant advantages in terms of low toxicity, chemical inertness, tunable fluorescence, good water solubility, and physicochemical properties as mentioned in this paper.
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Flexible Graphene-Based Wearable Gas and Chemical Sensors
TL;DR: The role of graphene in fabricating flexible gas sensors for the detection of various hazardous gases, including nitrogen dioxide, ammonia, hydrogen, hydrogen sulfide, carbon dioxide, sulfur dioxide, and humidity in wearable technology, is discussed.
Journal ArticleDOI
Promises, facts and challenges for graphene in biomedical applications
Giacomo Reina,Jose M. González-Domínguez,Alejandro Criado,Ester Vázquez,Alberto Bianco,Maurizio Prato +5 more
TL;DR: This Tutorial Review critically describes the latest developments of the graphene family materials into the biomedical field and analyzes graphene-based devices starting from graphene synthetic strategies, functionalization and processibility protocols up to the final in vitro and in vivo applications.
Journal ArticleDOI
A review on graphene-based nanocomposites for electrochemical and fluorescent biosensors
TL;DR: Graphene and its oxygenated derivatives, including reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the field of biosensors as discussed by the authors, and the discovery of graphene has spectacularly accelerated research on fabricating low-cost electrode materials because of its unique physical properties, including high specific surface area, high carrier mobility, high electrical conductivity, flexibility.
References
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Journal ArticleDOI
Graphene Oxide‐Based Antibacterial Cotton Fabrics
Jinming Zhao,Bo(邓波)) Deng,Min Lv,Jingye(李景烨) Li,Yujie Zhang,Haiqing Jiang,Cheng Peng,Jiang Li,Jiye Shi,Jiye Shi,Qing(黄庆) Huang,Chunhai(樊春海) Fan +11 more
TL;DR: It is believed that these flexible, foldable, and re-usable GO-based antibacterial cotton fabrics have high promise as a type of new nano-engineered antibacterial materials for a wide range of applications.
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Blood compatible graphene/heparin conjugate through noncovalent chemistry.
TL;DR: Graphene/UFH conjugate shows much enhanced anti factor Xa (FXa) activity of 29.6IU/mL compared with pristine graphene oxide (GO; 1.03 IU/mL).
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Three-dimensional graphene/Pt nanoparticle composites as freestanding anode for enhancing performance of microbial fuel cells.
Shenlong Zhao,Yuchen Li,Huajie Yin,Zhouzhou Liu,Enxiao Luan,Feng Zhao,Zhiyong Tang,Shaoqin Liu +7 more
TL;DR: A three-dimensional graphene aerogel (GA) decorated with platinum nanoparticles (Pt NPs) as an efficient freestanding anode for MFCs shows unprecedented performance and opens the avenue toward the real application of the M FCs.
Journal ArticleDOI
Surface Coating‐Dependent Cytotoxicity and Degradation of Graphene Derivatives: Towards the Design of Non‐Toxic, Degradable Nano‐Graphene
Yingjie Li,Liangzhu Feng,Xiaoze Shi,Xiaojing Wang,Yinlong Yang,Kai Yang,Teng Liu,Guangbao Yang,Zhuang Liu +8 more
TL;DR: In order to obtain biocompatible functionalized GO that can still undergo enzymatic degradation, PEG is conjugated to GO via a cleavable disulfide bond, obtaining GO-SS-PEG with negligible toxicity and considerable degradability, promising for further biomedical applications.
Journal ArticleDOI
Simultaneous Reduction and Surface Functionalization of Graphene Oxide for Hydroxyapatite Mineralization
Hongyan Liu,Pinxian Xi,Guoqiang Xie,Yanjun Shi,Fengping Hou,Liang Huang,Fengjuan Chen,Zhengzhi Zeng,Changwei Shao,Jun Wang +9 more
TL;DR: In this article, a reduced graphene oxide/hydroxyapatite (RGO/HA) hybrid material was synthesized by an environmental-friendly route, where Graphene oxide (GO) was first simultaneously reduced and surface functionalized by one-step oxidative polymerization of dopamine (PDA), which enabled efficient interaction between the RGO surface and the mineral ions to improve the bioactivity, promoted the formation of the HA nanoparticles.