Journal ArticleDOI
Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications
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TLDR
This review elucidate FGNs-bioorganism interactions and summarize recent advancements on designing FGN-based two-dimensional and three-dimensional architectures as multifunctional biological platforms.Abstract:
Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely unique physical and chemical properties and physiological ability to interfere and/or interact with bioorganisms; as a result, FGNs present manifold possibilities for diverse biological applications. Beyond their use in drug/gene delivery, phototherapy, and bioimaging, recent studies have revealed that FGNs can significantly promote interfacial biointeractions, in particular, with proteins, mammalian cells/stem cells, and microbials. FGNs can adsorb and concentrate nutrition factors including proteins from physiological media. This accelerates the formation of extracellular matrix, which eventually promotes cell colonization by providing a more beneficial microenvironment for cell adhesion and growth. Furthermore, FGNs can also interact with cocultured cells by physical or chemical stimulation, which significantly mediate their cellular signaling and biological performance. In this review, we elucidate FGNs–bioorganism int...read more
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Synthesis, properties, and applications of graphene oxide/reduced graphene oxide and their nanocomposites
TL;DR: In this paper, the authors review the synthesis techniques most commonly used to produce these graphene derivatives, discuss how synthesis affects their key material properties, and highlight some examples of nanocomposites with unique and impressive properties.
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Carbon dots: synthesis, formation mechanism, fluorescence origin and sensing applications
TL;DR: Carbon dots have received an increasing amount of attention because of their significant advantages in terms of low toxicity, chemical inertness, tunable fluorescence, good water solubility, and physicochemical properties as mentioned in this paper.
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Flexible Graphene-Based Wearable Gas and Chemical Sensors
TL;DR: The role of graphene in fabricating flexible gas sensors for the detection of various hazardous gases, including nitrogen dioxide, ammonia, hydrogen, hydrogen sulfide, carbon dioxide, sulfur dioxide, and humidity in wearable technology, is discussed.
Journal ArticleDOI
Promises, facts and challenges for graphene in biomedical applications
Giacomo Reina,Jose M. González-Domínguez,Alejandro Criado,Ester Vázquez,Alberto Bianco,Maurizio Prato +5 more
TL;DR: This Tutorial Review critically describes the latest developments of the graphene family materials into the biomedical field and analyzes graphene-based devices starting from graphene synthetic strategies, functionalization and processibility protocols up to the final in vitro and in vivo applications.
Journal ArticleDOI
A review on graphene-based nanocomposites for electrochemical and fluorescent biosensors
TL;DR: Graphene and its oxygenated derivatives, including reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the field of biosensors as discussed by the authors, and the discovery of graphene has spectacularly accelerated research on fabricating low-cost electrode materials because of its unique physical properties, including high specific surface area, high carrier mobility, high electrical conductivity, flexibility.
References
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Journal ArticleDOI
Superior Antibacterial Activity of Zinc Oxide/Graphene Oxide Composites Originating from High Zinc Concentration Localized around Bacteria
Yan-Wen Wang,Aoneng Cao,Jiang Yu,Xin Zhang,Jia-Hui Liu,Yuanfang Liu,Yuanfang Liu,Haifang Wang +7 more
TL;DR: The results indicate that the ZnO/GO composites are promising disinfection materials to be used in surface coatings on various substrates to effectively inhibit bacterial growth, propagation, and survival in medical devices.
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In vivo biodistribution and toxicology of functionalized nano-graphene oxide in mice after oral and intraperitoneal administration.
TL;DR: This work sought to systematically investigate in vivo biodistribution and potential toxicity of as-made GO and a number of polyethylene glycol (PEG) functionalized GO derivatives with different sizes and surface coatings, after oral and intraperitoneal administration at high doses.
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The Enzymatic Oxidation of Graphene Oxide
Gregg P. Kotchey,Brett L. Allen,Harindra Vedala,Naveena Yanamala,Alexander A. Kapralov,Yulia Y. Tyurina,Judith Klein-Seetharaman,Valerian E. Kagan,Alexander Star +8 more
TL;DR: The enzymatic oxidation of a single layer of graphitic carbon by horseradish peroxidase (HRP) resulted in the formation of holes on its basal plane, which rendered hRGO, which can be conceptualized as interconnected graphene nanoribbons, as a potentially attractive material for FET sensors.
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A Strong Integrated Strength and Toughness Artificial Nacre Based on Dopamine Cross-Linked Graphene Oxide
TL;DR: This paper has developed a strategy for fabricating the strong integrated artificial nacre based on graphene oxide (GO) sheets by dopamine cross-linking via evaporation-induced assembly process by showing tensile strength and toughness simultaneously show 1.5 and 2 times higher than that of natural nacre.