Journal ArticleDOI
GAP-43 expression in the medulla of macaque monkeys: changes during postnatal development and the effects of early median nerve repair.
TLDR
The results suggest that reorganization mechanisms at central terminals of peripheral nerves are very different following prenatal than postnatal nerve damage.About:
This article is published in Developmental Brain Research.The article was published on 1995-12-21. It has received 7 citations till now. The article focuses on the topics: Macaque & Cuneate nucleus.read more
Citations
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Journal ArticleDOI
The cortical somatotopic map and phantom phenomena in subjects with congenital limb atrophy and traumatic amputees with phantom limb pain
Pedro Montoya,Karin Ritter,Ellena Huse,Wolfgang Larbig,Christoph Braun,Stephanie Töpfner,Werner Lutzenberger,Wolfgang Grodd,Herta Flor,Niels Birbaumer,Niels Birbaumer +10 more
TL;DR: The assumption that congenital absence of a limb does not lead to cortical reorganization or phantom limbs is confirmed whereas traumatic amputations that are accompanied by phantom limb pain show shifts of the cortical areas adjacent to the amputation zone towards the representation of the deafferented body part.
Journal ArticleDOI
Central reorganization of sensory pathways following peripheral nerve regeneration in fetal monkeys.
TL;DR: It is shown that there is little or no topographic order in the median nerve to the hand after median nerve section and surgical repair in immature macaque monkeys, and in the same animals the representation of the reinnervated hand in primary somato-sensory cortēx is quite orderly.
Journal ArticleDOI
Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide‐incorporated collagen tubes
TL;DR: The combined results suggest that the early phase of regeneration of peripheral nerves in the presence of peptide‐incorporated collagen tubes results in the enhanced production of trophic factors by the recruited hematogenous cells and Schwann cells, which in turn help in the secretion of certain vital Trophic and tropic factors essential for early regeneration.
Journal ArticleDOI
Evidence for Altered Ca2+ Handling in Growth Associated Protein 43-Knockout Skeletal Muscle
Giusy A. Caprara,Caterina Morabito,Stefano Perni,Riccardo Navarra,Simone Guarnieri,Maria A. Mariggiò +5 more
TL;DR: GAP43 expression is involved in timing of muscle maturation in-vivo, and the emerging hypothesis indicates that GAP43 interacts with calmodulin to indirectly modulate the activities of dihydropyridine and ryanodine Ca2+ channels, from functional excitation-contraction coupling, to cell metabolism, and gene expression.
Journal ArticleDOI
Brain Reorganization and Experience
Jon H. Kaas,S. L. Florence +1 more
TL;DR: The ability to adjust to changes in the external environment is critical for learning and for recovery from brain injury as discussed by the authors, and the ability to respond in a reliable way is crucial for learning.
References
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Journal ArticleDOI
The projection of low-threshold muscle afferents of the forelimb to the main and external cuneate nuclei of the monkey.
TL;DR: The bulbar relay subserved by primary muscle afferents from the monkey's deep radial nerve was investigated by means of transganglionic labeling with wheatgerm agglutinin conjugated with horseradish peroxidase as well as by electrophysiological techniques.
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Maturation of fastest afferent and efferent central and peripheral pathways : no evidence for a constancy of central conduction delays
TL;DR: It is concluded that the prolonged maturational central conduction time precludes the usage of a fixed temporal timing pattern during development in the human sensory motor system.
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Reorganization of the peripheral projections of the trigeminal ganglion following neonatal transection of the infraorbital nerve.
Robert W. Rhoades,Nicolas L. Chiaia,R. D. Mooney,Bradley G. Klein,William E. Renehan,Mark F. Jacquin +5 more
TL;DR: In this paper, two different anatomical techniques were used to obtain evidence that transection of the infraorbital (IO) nerve on the day of birth would result in reorganization of the peripheral projections of the trigeminal nerve.
Journal ArticleDOI
Subdivisions of the visual system labeled with the Cat-301 antibody in tree shrews.
TL;DR: The monoclonal antibody Cat-301 was used to stain neurons and neuropil in the visual thalamus and cortex of tree shrews--small, highly visual mammals that are closely related to primates.
Journal ArticleDOI
The expression of B-50/GAP-43 during development of rat spinal neurons in culture is regulated by interneuronal contact.
TL;DR: It is concluded that B-50 expression is down-regulated by neurite-cell or cell-cell contact in spinal neurons offetal rat.
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