Journal ArticleDOI
Gastrinoma (duodenal and pancreatic)
Robert T. Jensen,Bruno Niederle,Emmanuel Mitry,John Ramage,Thomas Steinmüller,Val Lewington,Aldo Scarpa,Anders Sundin,Aurel Perren,David J. Gross,Juan Manuel O'Connor,Stanislas Pauwels,Günter Klöppel +12 more
TLDR
a Digestive Diseases Branch, NIH, Bethesda, Md, USA; b Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna , Austria; c Department of Hepatology and Gastroenterology, CHV A Pare Hospital, Boulogne , France; d Department of GastroEnterology, North Hampshire Hospital, Hampshire , UK.Abstract:
a Digestive Diseases Branch, NIH, Bethesda, Md. , USA; b Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna , Austria; c Department of Hepatology and Gastroenterology, CHV A Pare Hospital, Boulogne , France; d Department of Gastroenterology, North Hampshire Hospital, Hampshire , UK; e Department of Surgery, Vivantes Humboldt Hospital, Berlin , Germany; f Department of Radiology, Royal Marsden Hospital, Sutton , UK; g Department of Pathology, Verona University, Verona , Italy; h Department of Radiology, Uppsala University, Uppsala , Sweden; i Department of Pathology, Universitatsspital Zurich, Zurich , Switzerland; j Department of Endocrinology and Metabolism, Hadassah University, Jerusalem , Israel; k Department of Oncology, Alexander Fleming Institute, Buenos Aires , Argentina; l Laboratory of Molecular Imaging and Experimental Radiotherapy, Universite Catholique de Louvain, Brussels , Belgium; m Department of Pathology, University Hospital of Kiel, Kiel , Germanyread more
Citations
More filters
Journal ArticleDOI
ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors.
Massimo Falconi,Barbro Eriksson,Gregory Kaltsas,Detlef K. Bartsch,Jaume Capdevila,Martyn Caplin,Beata Kos-Kudła,Dirk Jan Kwekkeboom,Guido Rindi,Günter Klöppel,Nicholas Reed,Reza Kianmanesh,Robert T. Jensen +12 more
TL;DR: The ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatics with Functional and non-functional tumours is published.
Journal ArticleDOI
ENETS Consensus Guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary.
Marianne Pavel,Eric Baudin,Anne Couvelard,Eric P. Krenning,Kjell Öberg,Thomas Steinmüller,Martin Anlauf,Bertram Wiedenmann,Ramon Salazar +8 more
TL;DR: ENETS Consensus Guidelines for the Management of Patients with Liver and Other Distant Metastases from Neuroendocrine Neoplasms of Foregut, MidGut, Hind gut, and Unknown Primary
Journal ArticleDOI
Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors.
David C. Metz,Robert T. Jensen +1 more
TL;DR: A number of recent advances regarding the molecular pathology, diagnosis, localization, and management of PETs are addressed including discussion of peptide-receptor radionuclide therapy and other novel antitumor approaches and a discussion of future directions and unsettled problems in the field.
Book ChapterDOI
Pathology and Genetics
TL;DR: Local aggressiveness consists in the invasion of contiguous structures and organs (spleen, stomach, left adrenal gland, colon, and peritoneum), whereas distant metastases can occur in liver, lungs, adrenals, kidneys, bones, brain, and skin.
Journal ArticleDOI
ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes.
Robert T. Jensen,Guillaume Cadiot,Maria Luisa Brandi,Wouter W. de Herder,Gregory Kaltsas,Paul Komminoth,Jean-Yves Scoazec,Alain Sauvanet,Reza Kianmanesh +8 more
TL;DR: The two most common functional p-NETs (gastrinomas, insulinomas) are considered separately, whereas the other well-described and possible rarefunctional p- NETs are considered together as a group called rare functional rFTs (RFTs).
References
More filters
Journal ArticleDOI
Prospective, Randomized, Multicenter Trial on the Antiproliferative Effect of Lanreotide, Interferon Alfa, and Their Combination for Therapy of Metastatic Neuroendocrine Gastroenteropancreatic Tumors—The International Lanreotide and Interferon Alfa Study Group
Siegbert Faiss,Ulrich-Frank Pape,Michael Böhmig,Yvonne Dörffel,Ulrich Mansmann,Werner Golder,Ernst Otto Riecken,Bertram Wiedenmann +7 more
TL;DR: This prospective, randomized, multicenter study shows for the first time that somatostatin analogs, interferon alfa, or the combination of the two had comparable antiproliferative effects in the treatment of metastatic neuroendocrine gastroenteropancreatic tumors.
Journal ArticleDOI
Determinants of Metastatic Rate and Survival in Patients With Zollinger-Ellison Syndrome: A Prospective Long-term Study
H. Christian Weber,David Venzon,Jaw-Town Lin,Vitaly A. Fishbein,Murray Orbuch,Doris B. Strader,Fathia Gibril,David C. Metz,Douglas L. Fraker,Jeffrey A. Norton,Robert T. Jensen +10 more
TL;DR: Survival was primarily determined by the presence of liver metastases, and the frequency of Liver metastases depends on the size and location of the primary tumor and on the Presence of MEN-1 at the initial presentation.
Journal ArticleDOI
Surgery to cure the Zollinger-Ellison syndrome.
Jeffrey A. Norton,Douglas L. Fraker,H R Alexander,David Venzon,J L Doppman,Jose Serrano,Stephan U. Goebel,P L Peghini,Praveen K. Roy,Fathia Gibril,Robert T. Jensen +10 more
TL;DR: All patients with the Zollinger-Ellison syndrome who do not have multiple endocrine neoplasia type 1 or metastatic disease should be offered surgical exploration for possible cure.
Journal ArticleDOI
Somatostatin Receptor Scintigraphy: Its Sensitivity Compared with That of Other Imaging Methods in Detecting Primary and Metastatic Gastrinomas: A Prospective Study
Fathia Gibril,James C. Reynolds,John L. Doppman,Clara C. Chen,David Venzon,B Termanini,H C Weber,Chip Stewart,Robert T. Jensen +8 more
TL;DR: It is difficult for the practitioner to define the potential role of somatostatin receptor scintigraphy in the evaluation of a patient with a gastroenteropancreatic syndrome because many studies do not provide the data needed and it remains unclear whether additional localization studies are helpful.
Journal ArticleDOI
Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas
Michelle A. Anderson,Steven Carpenter,Norman W. Thompson,Timothy T. Nostrant,Grace H. Elta,James M. Scheiman +5 more
TL;DR: The results support the use of EUS as a primary diagnostic modality in the evaluation and management of patients with neuroendocrine tumors of the pancreas and show that EUS was more accurate than angiography with or without stimulation testing, transcutaneous ultrasound, and CT in those patients undergoing further imaging procedures.
Related Papers (5)
Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors.
David C. Metz,Robert T. Jensen +1 more