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Journal ArticleDOI

Gonadal effects on food intake and adiposity: a metabolic hypothesis.

George N. Wade, +1 more
- 01 Mar 1979 - 
- Vol. 22, Iss: 3, pp 583-593
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TLDR
It is suggested that during naturally-occurring reproductive states gonadal steroids interact with other hormones to partition available triglycerides among tissues which oxidize, excrete or store long-chain fatty acids, contributing to the changes in food intake.
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This article is published in Physiology & Behavior.The article was published on 1979-03-01. It has received 438 citations till now. The article focuses on the topics: Adipose tissue & Hormone.

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Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome

TL;DR: PCO women have significant insulin resistance that is independent of obesity, changes in body composition, and impairment of glucose tolerance, and PCO is associated with a unique disorder of insulin action.
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Increased adipose tissue in male and female estrogen receptor-α knockout mice

TL;DR: Evidence is found that estrogen/ERα signaling is critical in female and male WAT; obesity in αERKO males involves a mechanism of reduced energy expenditure rather than increased energy intake.
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Biological actions of androgens

TL;DR: Though unnecessary for life itself, androgens are essential for the propagation of the species and for establishment and maintenance of the quality of life of males through their support of sexual behavior and function, muscle strength, and sense of well-being.
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Testosterone Replacement in Older Hypogonadal Men: A 12-Month Randomized Controlled Trial

TL;DR: Testosterone supplementation improved strength, increased hemoglobin, and lowered leptin levels in older hypogonadal men in this patient population, and may have a role in the treatment of frailty in males with Hypogonadism.
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Sexual dimorphism in the control of growth hormone secretion.

TL;DR: A feminization of the liver develops after continuous, but not intermittent, administration of GH to hypophysectomized rats, suggesting that high, infrequent GH pulses with low plasma GH levels in between promotes growth more effectively than an intermediate, rather constant level of plasma GH.
References
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Journal ArticleDOI

Plasma Concentration of LH, FSH, Prolactin, Progesterone and Estradiol-17β Throughout the 4-Day Estrous Cycle of the Rat

TL;DR: Groups of female rats were decapitated at 3-hr intervals throughout 4-day estrous cycles and the plasma of each rat was assayed for LH, FSH, prolactin, progesterone and estradiol-17β, which exhibited a peak concentration in plasma on the day of proestrus.
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Female steroid hormones and target cell nuclei.

TL;DR: The data discussed herein demonstrate the great variation in target-tissue response that can occur after administration of steroid hormones, and direct quantitative evidence that sex steroids cause a net increase in the intracellular amounts of specific mRNA molecules in target tissues is provided.
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Current Models of Steroid Hormone Action: A Critique

TL;DR: In this review, the path of estradiol is traced from its entry into the cell to the time of its release from the receptor, with highlighted data that suggest the existence of a protein-mediated transport.
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