Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity
TLDR
The recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action are discussed.Abstract:
Since discovery of the first antibiotic drug, penicillin, in 1928, a variety of antibiotic and antimicrobial agents have been developed and used for both human therapy and industrial applications. However, excess and uncontrolled use of antibiotic agents has caused a significant growth in the number of drug resistant pathogens. Novel therapeutic approaches replacing the inefficient antibiotics are in high demand to overcome increasing microbial multidrug resistance. In the recent years, ongoing research has focused on development of nano-scale objects as efficient antimicrobial therapies. Among the various nanoparticles, silver nanoparticles have gained much attention due to their unique antimicrobial properties. However, concerns about the synthesis of these materials such as use of precursor chemicals and toxic solvents, and generation of toxic byproducts have led to a new alternative approach, green synthesis. This eco-friendly technique incorporates use of biological agents, plants or microbial agents as reducing and capping agents. Silver nanoparticles synthesized by green chemistry offer a novel and potential alternative to chemically synthesized nanoparticles. In this review, we discuss the recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action.read more
Citations
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Green Synthesis of Metallic Nanoparticles and Their Prospective Biotechnological Applications: an Overview
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TL;DR: This review will address biological entities that can be used for the green synthesis of NPs and their prospects for biotechnological applications.
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A review on the biosynthesis of metal and metal salt nanoparticles by microbes
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Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications
Maria Godoy-Gallardo,Ulrich Eckhard,Luis Delgado,Yolanda Puente,Mireia Hoyos-Nogués,F. Javier Gil,Roman A. Perez +6 more
TL;DR: In this paper, a comprehensive review on how metal ions and ion nanoparticles have the potential to decrease or eliminate unwanted bacteria is provided, including specific metal ions such as silver, zinc, copper, iron and gold.
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Wound dressings functionalized with silver nanoparticles: promises and pitfalls
Katayoon Kalantari,Ebrahim Mostafavi,Amalina M. Afifi,Zahra Izadiyan,Hossein Jahangirian,Roshanak Rafiee-Moghaddam,Thomas J. Webster +6 more
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Silver Nanoparticles: Mechanism of Action and Probable Bio-Application
TL;DR: This review is devoted to the medical application of silver nanoparticles produced as a result of “green” synthesis using various living organisms (bacteria, fungi, plants).
References
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TL;DR: This is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and the results demonstrate thatsilver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.