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Open AccessJournal ArticleDOI

Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice

TLDR
BaWeiBaiDuSan (BWBDS) was extracted from a formula of Panax ginseng C. A. Meyer, Lilium brownie F. E. Brown ex Miellez var. ex Redoute, Lonicera japonica Thunb, Hippophae rhamnoides Linn., Amygdalus Communis Vas, Platycodon grandiflorus (Jacq.) A. DC., and Cortex Phelloderdri as mentioned in this paper .
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This article is published in Acta Pharmaceutica Sinica B.The article was published on 2022-10-01 and is currently open access. It has received 3 citations till now. The article focuses on the topics: Medicine & Biology.

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Fecal microbiota transplantation holds the secret to youth

TL;DR: Fecal microbiota transplantation (FMT) as mentioned in this paper can reverse the effects of aging on the digestive system, the brain, and the vision by transplanting the functional bacteria found in the excrement of healthy individuals into the gut tracts of patients.
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LncRNA 220: A Novel Long Non-Coding RNA Regulates Autophagy and Apoptosis in Kupffer Cells via the miR-5101/PI3K/AKT/mTOR Axis in LPS-Induced Endotoxemic Liver Injury in Mice

TL;DR: In this article , a newly discovered lncRNA, named 220, was identified to function in regulating autophagy and apoptosis in Kupffer cells treated with lipopolysaccharide (LPS).
References
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Journal ArticleDOI

Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production.

TL;DR: It is suggested that cultured, banked human BMSCs may be effective in treating sepsis in high-risk patient groups because they have been successfully given to humans and can easily be cultured and might be used without human leukocyte antigen matching.
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The immunopathology of sepsis and potential therapeutic targets

TL;DR: Pivotal for the clinical development of new sepsis therapies is the selection of patients on the basis of biomarkers and/or functional defects that provide specific insights into the expression or activity of the therapeutic target.
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You are what you eat: diet, health and the gut microbiota.

TL;DR: The major principles underlying effects of dietary constituents on the gut microbiota are reviewed, resolving aspects of the diet–microbiota–host crosstalk, and the promises and challenges of incorporating microbiome data into dietary planning are presented.
Journal ArticleDOI

Inflammasome activation and IL-1β and IL-18 processing during infection

TL;DR: This review highlights alternative mechanisms for processing IL-1β and IL-18 during infection, which involve extracellular cleavage of the inactive cytokines by neutrophil-derived serine proteases or proteases released from cytotoxic T cells.
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