Heteropoly Acid in Ionic Liquid - An Efficient Catalyst for the Preparation of 2H-Indazolo(2,1-b)Phthalazine-Triones
TLDR
In this paper, H-Indazolo(2,1-b)phthalazine-1,6,11(13H)-trione derivatives were synthesized in a simple and efficient method from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes by H3PW12O40 in ionic liquid in good to excellent yields and short reaction times.Abstract:
H-Indazolo(2,1-b)phthalazine-1,6,11(13H)-trione derivatives were synthesized in a simple and efficient method from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes by H3PW12O40 in ionic liquid in good to excellent yields and short reaction times. The ionic liquid 1-butyl-3- methylimidazolium tetrafluoroborate ((bmim)BF4) offered the best results in terms of yield of the products. It was observed that a homogeneous reaction medium proved beneficial for the yield of the reaction.read more
Citations
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Update 1 of: Ionic liquids in heterocyclic synthesis.
Marcos A. P. Martins,Clarissa P. Frizzo,Aniele Z. Tier,Dayse N. Moreira,Nilo Zanatta,Helio G. Bonacorso +5 more
Journal ArticleDOI
Ultrasound-promoted catalyst-free one-pot four component synthesis of 2H-indazolo[2,1-b]phthalazine-triones in neutral ionic liquid 1-butyl-3-methylimidazolium bromide.
TL;DR: A catalyst-free one-pot four component methodology for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones under ultrasonic irradiation at room temperature using 1-butyl-3-methylimidazolium bromide, [Bmim]Br, as a neutral reaction medium is described.
Journal ArticleDOI
Microwave-assisted, montmorillonite K-10 catalyzed three-component synthesis of 2H-indazolo(2,1-b)phthalazine-triones under solvent-free conditions
TL;DR: In this paper, an efficient, rapid, and green synthesis of 2H -indazolo[2,1-b ]phthalazine-triones has been accomplished under solvent-free conditions by the reaction of phthalhydrazide, aldehydes and 5,5-dimethylcyclohexane-1,3-dione.
Journal ArticleDOI
A mesoporous SBA-15 silica catalyst functionalized with phenylsulfonic acid groups (SBA-15-Ph-SO3H) as a novel hydrophobic nanoreactor solid acid catalyst for a one-pot three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones and triazolo[1,2-a]indazole-triones
TL;DR: Phenyl sulfonic acid functionalized mesoporous SBA-15 silica (SBA15-Ph-SO3H) was prepared through the silanization of activated SBA15 with diphenyldichlorosilane (DPCS) followed by silylation and sulfonation, and characterized by XRD, FT-IR, nitrogen adsorption analyses, BET theory and TEM.
Journal ArticleDOI
Efficient CAN catalyzed synthesis of 1H-indazolo[1,2-b] phthalazine-1,6,11-triones: An eco-friendly protocol
TL;DR: In this paper, a one-pot protocol using phthalhydrazide, a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol is presented.
References
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Book ChapterDOI
Catalytic Chemistry of Heteropoly Compounds
TL;DR: The catalytic properties of heteropoly compounds have drawn wide attention, owing to the versatility of these compounds as catalysts, which has been demonstrated both by success in large-scale applications and by promising laboratory results as mentioned in this paper.
Journal ArticleDOI
Heteropoly Acids and Related Compounds as Catalysts for Fine Chemical Synthesis
TL;DR: In this article, a wide variety of HPAs belonging to the so-called Keggin series are the most important for catalysis and they include heteropolyanions (HPANs) which have metal-oxygen octahedra as the basic structural units.