Higher Serum Levels of Vitamin D Are Associated With a Reduced Risk of Diverticulitis
TLDR
Higher prediagnostic levels of 25(OH)D are associated significantly with a lower risk of diverticulitis, indicating that vitamin D deficiency could be involved in the pathogenesis of diverticsulitis.About:
This article is published in Clinical Gastroenterology and Hepatology.The article was published on 2013-12-01 and is currently open access. It has received 49 citations till now. The article focuses on the topics: Diverticulosis & vitamin D deficiency.read more
Citations
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Epidemiology, Pathophysiology, and Treatment of Diverticulitis
Lisa L. Strate,Arden M. Morris +1 more
TL;DR: Elective surgical resection is no longer recommended solely based on number of recurrent events or young patient age and might not be necessary for some patients with diverticulitis complicated by abscess, and randomized trials of hemodynamically stable patients who require urgent surgery provide evidence to support primary anastomosis vs sigmoid colectomy with end colostomy.
Journal ArticleDOI
Diverticular Disease: An Update on Pathogenesis and Management
TL;DR: Paradigms shifts in several areas of the pathogenesis and management of diverticular disease are explored in this review.
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Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.
Lillias H. Maguire,Samuel K. Handelman,Xiaomeng Du,Yanhua Chen,Tune H. Pers,Tune H. Pers,Elizabeth K. Speliotes +6 more
TL;DR: Genome-wide analyses identify 42 risk loci for diverticular disease and show that genes in associated regions are enriched for expression in connective tissue cell types and are coexpressed with genes involved in vascular and mesenchymal biology.
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Acute Colonic Diverticulitis
Sophia M. Swanson,Lisa L. Strate +1 more
TL;DR: The prevalence of diverticulitis in the United States has increased dramatically over the past several decades and is estimated to be 180 cases per 100000 persons per year; however, it is increasingly being seen in younger persons.
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Seasonal Variation in Emergency General Surgery.
Bardiya Zangbar,Peter Rhee,Viraj Pandit,Chiu Hsieh Hsu,Mazhar Khalil,Terence O'Keefe,Leigh Neumayer,Bellal Joseph +7 more
TL;DR: Hospitalization due to EGS adheres to a consistent cyclical pattern, with more admissions occurring during the Summer months, and this information may be useful for hospital resource reallocation and staffing.
References
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Burden of Gastrointestinal Disease in the United States: 2012 Update
Anne F. Peery,Evan S. Dellon,Jennifer L. Lund,Seth D. Crockett,Christopher E. McGowan,William J. Bulsiewicz,Lisa M. Gangarosa,Michelle T. Thiny,Karyn Stizenberg,Douglas R. Morgan,Yehuda Ringel,Hannah P. Kim,Marco Dacosta Dibonaventura,Charlotte F. Carroll,Jeffery K. Allen,Suzanne F. Cook,Robert S. Sandler,Michael D. Kappelman,Nicholas J. Shaheen +18 more
TL;DR: The burden of GI disease in the United States is estimated and the most common GI symptom is abdominal pain, while the total cost for outpatient GI endoscopy examinations was $32.4 billion.
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Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations:a nested case-control study
Mazda Jenab,H. Bas Bueno-de-Mesquita,Pietro Ferrari,Fränzel J.B. Van Duijnhoven,Teresa Norat,Tobias Pischon,Eugene Jansen,Nadia Slimani,Graham Byrnes,Sabina Rinaldi,Anne Tjønneland,Anja Olsen,Kim Overvad,Marie-Christine Boutron-Ruault,Françoise Clavel-Chapelon,Sophie Morois,Rudolf Kaaks,Jakob Linseisen,Heiner Boeing,Manuela M. Bergmann,Antonia Trichopoulou,Gesthimani Misirli,Dimitrios Trichopoulos,Franco Berrino,Paolo Vineis,Salvatore Panico,Domenico Palli,Rosario Tumino,Martine M. Ros,Carla H. van Gils,Petra H.M. Peeters,Magritt Brustad,Eiliv Lund,María J. Tormo,Eva Ardanaz,Laudina Rodríguez,María José Sánchez,Miren Dorronsoro,Carlos A. González,Göran Hallmans,R. Palmqvist,Andrew W. Roddam,Timothy J. Key,Kay-Tee Khaw,Philippe Autier,Pierre Hainaut,Elio Riboli +46 more
TL;DR: The results of this large observational study indicate a strong inverse association between levels of pre-diagnostic 25-(OH)D concentration and risk of colorectal cancer in western European populations.
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Higher Predicted Vitamin D Status Is Associated With Reduced Risk of Crohn's Disease
Ashwin N. Ananthakrishnan,Hamed Khalili,Leslie M. Higuchi,Ying Bao,Joshua R. Korzenik,Edward Giovannucci,James M. Richter,Charles S. Fuchs,Charles S. Fuchs,Andrew T. Chan,Andrew T. Chan +10 more
TL;DR: Higher predicted plasma levels of 25(OH)D significantly reduce the risk for incident CD and nonsignificant reduction in UC in women, and there was a significant inverse association between dietary and supplemental vitamin D and UC.
Journal ArticleDOI
Burden of digestive diseases in the United States part II: lower gastrointestinal diseases
Journal ArticleDOI
Obesity Increases the Risks of Diverticulitis and Diverticular Bleeding
Lisa L. Strate,Lisa L. Strate,Yan L. Liu,Walid H. Aldoori,Sapna Syngal,Sapna Syngal,Edward Giovannucci +6 more
TL;DR: In this large prospective cohort study of 47,228 male health professionals, BMI, waist circumference, and waist-to-hip ratio significantly increased the risks of diverticulitis and diverticular bleeding.