Journal ArticleDOI
Hydrodynamics and protein hydration.
Phil G. Squire,Michael E. Himmel +1 more
TLDR
A model of hemispherical clathrate cages is proposed which if correct, would account for the differences in the data obtained by these two methods, and a weak correlation between the number of apolar residues and hydrodynamic hydration is found.About:
This article is published in Archives of Biochemistry and Biophysics.The article was published on 1979-08-01. It has received 285 citations till now. The article focuses on the topics: Globular protein.read more
Citations
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Journal ArticleDOI
Average protein density is a molecular-weight-dependent function.
TL;DR: It is concluded that the average density of proteins is not a constant as often assumed and a simple molecular‐weight‐depending function is proposed that provides a more accurate estimate of the average protein density.
Journal ArticleDOI
Water Dynamics in the Hydration Shells of Biomolecules
TL;DR: Progress in theory and molecular dynamics simulations as well as in ultrafast vibrational spectroscopy has led to new and detailed insight into fluctuations of water structure, elementary water motions, electric fields at hydrated biointerfaces, and processes of vibrational relaxation and energy dissipation.
Journal ArticleDOI
Volume changes on protein folding.
TL;DR: The exceptionally high density of the protein interior shown here implies that packing forces play a more important role in protein stability than has been believed hitherto.
Journal ArticleDOI
The packing density in proteins: standard radii and volumes.
TL;DR: This analysis shows that, if the surface water molecules are included in the calculations, the overall packing efficiency throughout the protein interior is high and fairly uniform, but if the water structure is removed, the packing efficiency in peripheral regions of theprotein interior is underestimated.
Journal ArticleDOI
Characterization of the cytoplasm of Escherichia coli K-12 as a function of external osmolarity. Implications for protein-DNA interactions in vivo.
TL;DR: The water-accessible volumes, the amounts of all significant osmolytes, and the protein concentration in the cytoplasm of aerobically grown Escherichia coli K-12 have been determined as a function of the osmolarity of the minimal growth medium as discussed by the authors.
References
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Journal ArticleDOI
Superoxide Dismutase AN ENZYMIC FUNCTION FOR ERYTHROCUPREIN (HEMOCUPREIN)
Joe M. McCord,Irwin Fridovich +1 more
TL;DR: The demonstration that O2·- can reduce ferricytochrome c and tetranitromethane, and that superoxide dismutase, by competing for the superoxide radicals, can markedly inhibit these reactions, is demonstrated.
Journal ArticleDOI
The Protein Data Bank: a computer-based archival file for macromolecular structures.
Frances C. Bernstein,Thomas F. Koetzle,Graheme J. B. Williams,Edgar F. Meyer,Michael D. Brice,John R. Rodgers,O. Kennard,Takehiko Shimanouchi,Mitsuo Tasumi +8 more
TL;DR: The Protein Data Bank is a computer-based archival file for macromolecular structures that stores in a uniform format atomic co-ordinates and partial bond connectivities, as derived from crystallographic studies.
Journal ArticleDOI
Areas, volumes, packing and protein structure.
TL;DR: This review is concerned with the packing of groups of atoms in proteins and with the area of solvent-protein interfaces.