Journal ArticleDOI
Hydrogel nanoparticles for drug delivery.
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This article is published in Nanomedicine: Nanotechnology, Biology and Medicine.The article was published on 2013-11-01. It has received 233 citations till now. The article focuses on the topics: Drug delivery.read more
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Hydrogel: Preparation, characterization, and applications: A review
TL;DR: A review of the literature concerning classification of hydrogels on different bases, physical and chemical characteristics of these products, and technical feasibility of their utilization is presented in this paper, together with technologies adopted for hydrogel production together with process design implications, block diagrams, and optimized conditions of the preparation process.
Journal ArticleDOI
Hydrogels for Biomedical Applications: Their Characteristics and the Mechanisms behind Them
Qinyuan Chai,Yang Jiao,Xinjun Yu +2 more
TL;DR: Advantages of the hydrogels that overcome the limitations from other types of biomaterials will be discussed, and attention will be given to biomedical applications of different kinds of hydrogel including cell culture, self-healing, and drug delivery.
Journal ArticleDOI
Biopolymer-based nanoparticles for drug/gene delivery and tissue engineering.
Sachiko Nitta,Keiji Numata +1 more
TL;DR: In this article, a review of fabrication of biocompatible nanoparticles consisting of biopolymers such as protein (silk, collagen, gelatin, β-casein, zein and albumin), protein-mimicked polypeptides and polysaccharides (chitosan, alginate, pullulan, starch and heparin).
Journal ArticleDOI
Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery.
TL;DR: This paper presents a meta-analyses of the chiral stationary phase replacement process and its applications in bioreactor engineering and nanofiltration .
Journal ArticleDOI
Applications and Emerging Trends of Hyaluronic Acid in Tissue Engineering, as a Dermal Filler, and in Osteoarthritis Treatment
Amir Fakhari,Cory Berkland +1 more
TL;DR: This review addresses the distribution, turnover and tissue-specific properties of HA and considers recent products and strategies for modifying the viscoelastic properties ofHA in tissue engineering, as a dermal filler and in osteoarthritis treatment.
References
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Journal ArticleDOI
Geometric cues for directing the differentiation of mesenchymal stem cells.
TL;DR: The role that geometric shape cues can play in orchestrating the mechanochemical signals and paracrine/autocrine factors that can direct MSCs to appropriate fates is pointed to.
Journal ArticleDOI
Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency
Rebecca J. McMurray,Nikolaj Gadegaard,P. Monica Tsimbouri,Karl Burgess,Laura E. McNamara,Rahul S. Tare,Kate Murawski,Emmajayne Kingham,Richard O.C. Oreffo,Richard O.C. Oreffo,Matthew J. Dalby +10 more
TL;DR: The study identifies a nanostructured surface that retains stem-cell phenotype and maintains stem- cell growth over eight weeks, and implicates a role for small RNAs in repressing key cell signalling and metabolomic pathways, demonstrating the potential of surfaces as non-invasive tools with which to address the stem cell niche.
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Metabolic oxidation regulates embryonic stem cell differentiation
Oscar Yanes,Julie Clark,Diana M. Wong,Gary J. Patti,Antonio Sánchez-Ruiz,H. Paul Benton,Sunia A. Trauger,Caroline Desponts,Sheng Ding,Gary Siuzdak +9 more
TL;DR: It is demonstrated that the stem cell redox status is regulated during differentiation and postulate that the highly unsaturated metabolome sustained by stem cells makes them particularly attuned to differentiate in response to in vivo oxidative processes such as inflammation.