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Open AccessJournal ArticleDOI

Immunomodulatory peptides—A promising source for novel functional food production and drug discovery

- 01 Feb 2022 - 
- Vol. 148, pp 170696-170696
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TLDR
In this article , immunomodulatory peptides are used in vaccines as adjuvants which would be extremely desirable, especially in response to pandemics, in order to provide valuable suplements of novel functional food preparation and/or as precursors or active ingredients for drugs design for treatment variety of conditions arising from impaired function of immune system.
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This article is published in Peptides.The article was published on 2022-02-01 and is currently open access. It has received 23 citations till now. The article focuses on the topics: Antimicrobial peptides & Immune system.

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Review on plant-derived bioactive peptides: biological activities, mechanism of action and utilizations in food development

TL;DR: A review of plant-derived bioactive peptides can be found in this paper , where the mechanism of action and structure-activity relationships of the peptide were described, when known, and the major challenges and prospect in the application of the plant-derive peptides in the development of functional products are discussed and summarized.
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Biological activities of peptides obtained by pepsin hydrolysis of fishery products

TL;DR: A review of the use of pepsin as a catalyst in the production of bioactive peptides from fishery products can be found in this article , with special emphasis on the description of each reported biological properties, as well as some uses that have been explored for these peptides.
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Kiwicha (Amaranthus caudatus L.) protein hydrolysates reduce intestinal inflammation by modulating the NLRP3 inflammasome pathway.

TL;DR: The biological activity of two kiwicha (Amaranthus caudatus L.) protein hydrolysates obtained with the aid of Bioprotease LA-660 is explored regarding their anti-inflammatory response at the intestinal level, employing the CACO-2 cell line.
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New perspectives on fabrication of peptide-based nanomaterials in food industry: A review

TL;DR: In this article , a comprehensive overview of bioactivity and self-assembly properties of peptides is provided and the fabrication strategy and application prospects of self-assembling bioactive peptide-based materials are introduced.
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MPMABP: A CNN and Bi-LSTM-Based Method for Predicting Multi-Activities of Bioactive Peptides

TL;DR: A convolution neural network and bi-directional long short-term memory-based deep learning method for recognizing multi-activities of bioactive peptides and the empirical results showed that the MPMABP is superior to the state-of-the-art methods.
References
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Journal ArticleDOI

NF-κB: a key role in inflammatory diseases

TL;DR: The specificity of various NF-κB proteins, their role in inflammatory disease, the regulation of NF-β proteins and IκB activity by IκBs and IkkB kinase, and the development of therapeutic strategies aimed at inhibition are discussed.
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Role of the Microbiota in Immunity and Inflammation

TL;DR: In high-income countries, overuse of antibiotics, changes in diet, and elimination of constitutive partners, such as nematodes, may have selected for a microbiota that lack the resilience and diversity required to establish balanced immune responses.
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Sex differences in immune responses

TL;DR: It is emphasized that sex is a biological variable that should be considered in immunological studies and contribute to variations in the incidence of autoimmune diseases and malignancies, susceptibility to infectious diseases and responses to vaccines in males and females.
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Of mice and not men: differences between mouse and human immunology

TL;DR: Known discrepancies in both innate and adaptive immunity are outlined, including balance of leukocyte subsets, defensins, Toll receptors, inducible NO synthase, the NK inhibitory receptor families Ly49 and KIR, FcR, Ig subsets andChemokine and chemokine receptor expression.
Journal ArticleDOI

Defensins: antimicrobial peptides of innate immunity.

TL;DR: This review, inspired by a spate of recent studies ofdefensins in human diseases and animal models, focuses on the biological function of defensins.
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