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Book ChapterDOI

Improving Bioavailability of Vitamin A in Food by Encapsulation: An Update

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TLDR
This chapter is an update of the principal encapsulation techniques adopted for the development of vitamin A nanomaterials to improve its bioavailability and associated challenges with fabrication method.
Abstract
Vitamin A is an obligatory micronutrient for healthy human life as it cannot be synthesized de novo and has to be acquired from dietary sources. The poor water solubility and susceptibility against photochemical degradation make vitamin A relatively unstable during food processing as well as storage. To combat prevailing vitamin A deficiency, various strategies have already been adopted in pharmaceutical industries to develop vitamin A formulation which has the ability to protect and minimize its degradation. On the one hand, in pharmaceutical formulations, vitamin A may be coupled with sub-toxic effects due to its buildup in the liver and other vital organ, while on the other hand its involvement against various health disorders such as neurodegenerative diseases, cardiovascular diseases and cancer has recently compelled the population to achieve vitamin A via pharmaceutical supplements, functional foods or food supplements. The success of pharmaceutical application encouraged food technologists to develop numerous premixes encapsulating vitamin A appropriately which can be successfully applied for the development of food supplements or vitamin A-rich functional foods. So this chapter is an update of the principal encapsulation techniques adopted for the development of vitamin A nanomaterials to improve its bioavailability and associated challenges with fabrication method.

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Citations
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Journal ArticleDOI

Influence of Proteins on the Absorption of Lipophilic Vitamins, Carotenoids and Curcumin - A Review.

TL;DR: The functional properties of proteins, their chemical interactions with enzymes and food constituents during gastro-intestinal digestion, potentials and limitations for their use as emulsifiers are emphasized and data from human, animal and in vitro trials are summarized.
Journal ArticleDOI

Vitamin A Status Improvement in Obesity: Findings and Perspectives Using Encapsulation Techniques

TL;DR: In this article, the associations between vitamin A consumption and its precursors, encapsulated or not, and its physiological effects on obesity have been studied, showing that encapsulation presents an alternative capable of increasing vitamin A stability in the face of unfavorable conditions in the environment, which can reduce its functionality.
Book ChapterDOI

Food Applications of Cyclodextrins

TL;DR: In this paper, a narrative review on the cyclodextrin with emphasis given physico-chemical properties and ability to form inclusion complex is presented, and the current state-of-the-art on their utilization in the food industry as an encapsulating material for bioactive compounds is reviewed.
Book ChapterDOI

Micro/Nanoencapsulation of Active Food Compounds: Encapsulation, Characterization and Biological Fate of Encapsulated Systems

TL;DR: In this article, the current know-how and approaches for the production of micro-nano-encapsulation systems for active food compounds and application in new generation foods along with their future progress are discussed.
Book ChapterDOI

Ultrasonication and Food-Grade Nano-Materials

TL;DR: In this article, the authors presented some potential uses and benefits of nano-technology and ultrasound in food industry, including the ability of ultrasound to enhance the diffusion of micro-encapsulated fatty acids into the meat.
References
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Journal ArticleDOI

Effect of relative humidity on retention and stability of vitamin a microencapsulated by spray drying

TL;DR: In this article, the influence of relative humidity (RH) levels on the retention of the vitamin A was evaluated during storage and the retention showed significant difference with increasing RH levels (33, 60 and 86%) (P < 0.05).
Journal ArticleDOI

Biopharmaceutics of 13-cis-retinoic acid (isotretinoin) formulated with modified β-cyclodextrins

TL;DR: It is found that 13-cis-RA was eliminated from the body through a dose-independent process after intravenous injection of either sodium salt or the HP-beta-CD formulation within the tested dosage range and the bioavailability remained unchanged.
Journal ArticleDOI

Biopolymer nanoparticles for vehiculization and photochemical stability preservation of retinol

TL;DR: It was observed that HMP deposition on protein-RET nanocomplex surface improved the RET photochemical stability, and information derived from this work could be extrapolated for vehiculization and protection of other photosensitive lipophilic compounds.
Journal ArticleDOI

A robust experimental design method to optimize formulations of retinol solid lipid nanoparticles.

TL;DR: A robust experimental design method was developed using a response surface methodology and models to facilitate the development process of retinol solid lipid nanoparticles and a model for maximizing the overall desirability represented by the geometric mean of all objectives was found to provide a better solution.
Journal ArticleDOI

A novel multi-tiered experimental approach unfolding the mechanisms behind cyclodextrin-vitamin inclusion complexes for enhanced vitamin solubility and stability.

TL;DR: In this article, a mechanistic account for understanding the synthesis, characterization and solubility phenomena of vitamin complexes with cyclodextrins (CD) for enhanced solubilities and stability employing experimental and in silico molecular modeling strategies was provided.
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What are ways to increase the bioavailability of Vitamin A?

The paper discusses the use of encapsulation techniques to improve the bioavailability of Vitamin A in food.