Journal ArticleDOI
Individualized Metabolic Surgery Score: Procedure Selection Based on Diabetes Severity.
Ali Aminian,Stacy A. Brethauer,Amin Andalib,Amy S. Nowacki,Amanda Jiménez,Ricard Corcelles,Zubaidah Nor Hanipah,Suriya Punchai,Deepak L. Bhatt,Sangeeta R. Kashyap,Bartolome Burguera,Antonio M. Lacy,Josep Vidal,Philip R. Schauer +13 more
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TLDR
This is the largest reported cohort with long-term postoperative glycemic follow-up, which categorizes T2DM into 3 validated severity stages for evidence-based procedure selection, and categorizes RYGB was significantly more effective than SG, likely related to its more pronounced neurohormonal effects.Abstract:
Objective:To construct and validate a scoring system for evidence-based selection of bariatric and metabolic surgery procedures according to severity of type 2 diabetes (T2DM).Background:Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) account for >95% of bariatric procedures in United Stread more
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Revisional Surgeries of Laparoscopic Sleeve Gastrectomy
TL;DR: A review mainly describes the revisional surgeries of Laparoscopic sleeve gastrectomy (LSG), including the indication, choice of surgical method, and subsequent effect as discussed by the authors, including the impact of revision surgery on patients with morbid obesity due to restrictive and endocrine mechanisms.
Journal ArticleDOI
Comparison of Preoperative Remission Scores and Diabetes Duration Alone as Predictors of Durable Type 2 Diabetes Remission and Risk of Diabetes Complications After Bariatric Surgery: A Post Hoc Analysis of Participants From the Swedish Obese Subjects Study.
Kajsa Sjöholm,Lena M. S. Carlsson,Magdalena Taube,Carel W. le Roux,Per-Arne Svensson,Markku Peltonen,Markku Peltonen +6 more
TL;DR: Remission scores and diabetes duration are good predictors of short-term diabetes remission, however, for durable remission and risk of complications, remission scores andabetes duration alone have limited predictive ability.
Journal ArticleDOI
Metabolomic Profiles Predict Diabetes Remission after Bariatric Surgery.
Jane Ha,Mi Jang,Yeong Keun Kwon,Young Suk Park,Do Joong Park,Joo Ho Lee,Hyuk Joon Lee,Tae Kyung Ha,Yong Jin Kim,Sang Moon Han,Sang-Uk Han,Yoon Seok Heo,Sungsoo Park +12 more
TL;DR: The AAM profile predicts T2D remission after bariatric surgery more effectively than the existing prediction models.
Journal ArticleDOI
Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes.
TL;DR: Key knowledge gaps, particularly on long-term complications, microvascular- and macrovascular events, and mortality should be addressed, so treatment with RYGB can be applied in an individualized approach to maximize benefits and minimize complications.
Journal ArticleDOI
Review, Performance Comparison, and Validation of Models Predicting Type 2 Diabetes Remission After Bariatric Surgery in a Western European Population
TL;DR: In this paper, the authors compared the performance of pre-operatively predicting T2DM remission in a Western population one year after surgery and explored their predictive value in comparison to a model specifically designed for the study population.
References
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Journal ArticleDOI
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
Philip R. Schauer,Deepak L. Bhatt,John P. Kirwan,Kathy Wolski,Ali Aminian,Stacy A. Brethauer,Sankar D. Navaneethan,Rishi P. Singh,Claire E. Pothier,Steven E. Nissen,Sangeeta R. Kashyap +10 more
TL;DR: Five‐year outcome data showed that, among patients with type 2 diabetes and a BMI of 27 to 43, bariatric surgery plus intensive medical therapy was more effective thanintensive medical therapy alone in decreasing, or in some cases resolving, hyperglycemia.
Journal ArticleDOI
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 3-Year Outcomes
Philip R. Schauer,Deepak L. Bhatt,John P. Kirwan,Kathy Wolski,Stacy A. Brethauer,Sankar D. Navaneethan,Ali Aminian,Claire E. Pothier,Steven E. Nissen,Sangeeta R. Kashyap,Abstr Act +10 more
TL;DR: Among obese patients with uncontrolled type 2 diabetes, 3 years of intensive medical therapy plus bariatric surgery resulted in glycemic control in significantly more patients than did medical therapy alone.
Journal ArticleDOI
Bariatric-metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial
Geltrude Mingrone,Geltrude Mingrone,Simona Panunzi,Andrea De Gaetano,Caterina Guidone,Amerigo Iaconelli,Giuseppe Nanni,Marco Castagneto,Stefan R. Bornstein,Francesco Rubino +9 more
TL;DR: Surgery is more effective than medical treatment for the long-term control of obese patients with type 2 diabetes and should be considered in the treatment algorithm of this disease, however, continued monitoring of glycaemic control is warranted because of potential relapse of hyperglycaemia.
Journal ArticleDOI
How Do We Define Cure of Diabetes
John B. Buse,Sonia Caprio,William T. Cefalu,Antonio Ceriello,Stefano Del Prato,Silvio E. Inzucchi,Sue McLaughlin,Gordon L. Phillips,R. Paul Robertson,Francesco Rubino,Richard Kahn,M. Sue Kirkman +11 more
TL;DR: A consensus group of experts comprised of experts in pediatric and adult endocrinology, diabetes education, transplantation, metabolism, bariatric/metabolic surgery, and (for another perspective) hematology-oncology met in June 2009 to discuss issues.
Journal ArticleDOI
Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations
Francesco Rubino,David M. Nathan,Robert H. Eckel,Philip R. Schauer,K. George M.M. Alberti,Paul Zimmet,Stefano Del Prato,Linong Ji,Shaukat Sadikot,William H. Herman,Stephanie A. Amiel,Lee M. Kaplan,Gaspar Taroncher-Oldenburg,David E. Cummings +13 more
TL;DR: Although additional studies are needed to further demonstrate long-term benefits, there is sufficient clinical and mechanistic evidence to support inclusion of metabolic surgery among antidiabetes interventions for people with T2D and obesity.