Journal ArticleDOI
Influence of chitosan and hydroxyapatite incorporation on properties of electrospun PVA/HA nanofibrous mats for bone tissue regeneration: Nanofibers optimization and in-vitro assessment
Samar A. Salim,Samah A. Loutfy,Samah A. Loutfy,Esmail M. El-Fakharany,Tarek H. Taha,Yasmen Hussien,Elbadawy A. Kamoun +6 more
TLDR
Findings support the ability for using PVA/HA/CH/HAP NFs as biomaterials for bone tissue regeneration soon as they improve significantly their mechanical/thermal stability and relatively hindered swelling index, compared to mats without HAP.About:
This article is published in Journal of Drug Delivery Science and Technology.The article was published on 2021-04-01. It has received 26 citations till now. The article focuses on the topics: Nanofiber & Biomaterial.read more
Citations
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Journal ArticleDOI
Recent advances in PVA-polysaccharide based hydrogels and electrospun nanofibers in biomedical applications: A review.
TL;DR: In this paper, modern perspectives of synthesized/developed electrospun nanofibrous hydrogel membranes based popular carbohydrate polymers blend PVA which recently have been employed for versatile biomedical applications particularly wound dressings, were discussed intensively and compared in detail with traditional fabricated membranes based films, as well.
Journal ArticleDOI
Bone tissue engineering: Anionic polysaccharides as promising scaffolds.
Ponnurengam Malliappan Sivakumar,Abuzer Alp Yetisgin,Sevilay Burcu Sahin,Ebru Demir,Sibel Cetinel +4 more
TL;DR: Bone repair is a self-healing process as mentioned in this paper , and critical-sized bone defects need bone augmentation where bone tissue engineering plays vital role. Bone tissue Engineering (BTE) requires unique combinations of scaffolds, cells, and bio-signal molecules.
Journal ArticleDOI
Recent Advances in Hydroxyapatite-Based Biocomposites for Bone Tissue Regeneration in Orthopedics
TL;DR: This review summarizes recent advances in HA-based biocomposites for bone regeneration, addressing the most widely employed inorganic matrices, the natural and synthetic polymers used as reinforcing components, and the crosslinkers added to improve the mechanical properties of the scaffolds.
Journal ArticleDOI
Hyaluronic acid and chitosan-based electrospun wound dressings: Problems and solutions.
TL;DR: In this paper , the biological roles and mechanisms of chitosan and hyaluronic acid in the wound healing process are explained including the advantages of nanofibers for ideal wound management using the common solvents, copolymers enhancing spinning process, and the most biologically active incorporated substances thereby providing drug delivery in wound healing.
Journal ArticleDOI
Inorganic Nanoparticles in Bone Healing Applications
Alexandra-Cristina Burdusel,Oana Gherasim,Ecaterina Andronescu,Alexandru Mihai Grumezescu,Anton Ficai +4 more
TL;DR: This review aims to lay out the tremendous outcomes of using inorganic nanoparticles in bone healing applications, including bone repair and regeneration, and modern therapeutic strategies for bone-related pathologies.
References
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TL;DR: An overview of bone grafts and graft substitutes available for clinical applications is presented and osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold are provided.
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Chitosan-based biomaterials for tissue engineering
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A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications.
TL;DR: The purpose of this review is to evaluate the available published information on PVA with respect to its safety as a medical device implant material for cartilage replacement and the safety recommendation involving the further development of PVA cryogels forcartilage replacement is addressed.
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3D cell culture systems: advantages and applications.
TL;DR: The three dimensional way of culturing cells, their advantages, the scaffolds and matrices currently available, and the applications of such cultures in major areas of life sciences are reviewed.
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Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering.
TL;DR: The results show that n-HA/PA composite scaffolds exhibit good biocompatibility and extensive osteoconductivity with host bone, and the introduction of MSCs to the scaffolds dramatically enhanced the efficiency of new bone formation, especially at the initial stage after implantation.