Influence of Sex and Hormone Status on Circulating Natriuretic Peptides
Carolyn S.P. Lam,Carolyn S.P. Lam,Carolyn S.P. Lam,Susan Cheng,Susan Cheng,Karen Choong,Martin G. Larson,Martin G. Larson,Joanne M. Murabito,Christopher Newton-Cheh,Christopher Newton-Cheh,Shalender Bhasin,Elizabeth L. McCabe,Elizabeth L. McCabe,Karen K. Miller,Margaret M. Redfield,Ramachandran S. Vasan,Ramachandran S. Vasan,Andrea D. Coviello,Andrea D. Coviello,Thomas J. Wang,Thomas J. Wang +21 more
TLDR
Findings suggest that lower levels of circulating androgens and the potentiating effect of exogenous female hormone therapy contribute to the higher circulating NT-proBNP concentrations in women.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2011-08-02 and is currently open access. It has received 133 citations till now. The article focuses on the topics: Hormone therapy & Transgender hormone therapy.read more
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Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure with Preserved Ejection Fraction
TL;DR: Obesity-related HFpEF is a genuine form of cardiac failure and a clinically relevant phenotype that may require specific treatments, and is a viable candidate for phenotyping.
Journal ArticleDOI
Sex Differences in Heart Failure
Carolyn S.P. Lam,Clare Arnott,A. Beale,Chanchal Chandramouli,Denise Hilfiker-Kleiner,David M. Kaye,Bonnie Ky,Bernadet T. Santema,Karen Sliwa,Adriaan A. Voors +9 more
TL;DR: This review outlines the key sex differences with respect to clinical characteristics, pathophysiology, and therapeutic responses to HF treatments and addresses important differences in the prognosis of HF.
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Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary.
Sanjiv J. Shah,Barry A. Borlaug,Dalane W. Kitzman,Andrew D. McCulloch,Burns C. Blaxall,Rajiv Agarwal,Julio A. Chirinos,Sheila Collins,Rahul C. Deo,Mark T. Gladwin,Henk Granzier,Scott L. Hummel,David A. Kass,Margaret M. Redfield,Flora Sam,Thomas J. Wang,Patrice Desvigne-Nickens,Bishow B. Adhikari +17 more
TL;DR: The research priorities outlined in this document are meant to stimulate scientific advances in HFpEF by providing a road map for future collaborative investigations among a diverse group of scientists across multiple domains.
Journal ArticleDOI
Effects of Sacubitril-Valsartan Versus Valsartan in Women Compared With Men With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF.
John J.V. McMurray,Alice M Jackson,Carolyn S.P. Lam,Carolyn S.P. Lam,Carolyn S.P. Lam,Margaret M. Redfield,Inder S. Anand,Junbo Ge,Marty P. Lefkowitz,Aldo P. Maggioni,Felipe Martinez,Milton Packer,Marc A. Pfeffer,Burkert Pieske,Adel R. Rizkala,Shalini V. Sabarwal,Amil M. Shah,Sanjiv J. Shah,Victor Shi,Dirk J. van Veldhuisen,Faiez Zannad,Michael R. Zile,Maja Cikes,Eva Goncalvesova,Tzvetana Katova,Annamaria Kosztin,Małgorzata Lelonek,Nancy K. Sweitzer,Orly Vardeny,Brian Claggett,Pardeep S. Jhund,Scott D. Solomon +31 more
TL;DR: As compared with valsartan, sacubitril-valsartan seemed to reduce the risk of heart failure hospitalization more in women than in men, but the present study does not provide a definite mechanistic basis for this finding.
Journal ArticleDOI
Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction
Mauro Gori,Carolyn S.P. Lam,Deepak K. Gupta,Angela B. S. Santos,Susan Cheng,Amil M. Shah,Brian Claggett,Michael R. Zile,Elisabeth Kraigher-Krainer,Burkert Pieske,Adriaan A. Voors,Milton Packer,Toni Bransford,Martin Lefkowitz,John J.V. McMurray,Scott D. Solomon +15 more
TL;DR: The relationship between sex and cardiovascular structure and function in patients with HFpEF is studied to find out if women are more likely to develop heart failure with preserved ejection fraction than men.
References
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