Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage
Adnan I. Qureshi,Yuko Y. Palesch,William G. Barsan,Daniel F. Hanley,Chung Y. Hsu,Renee L. Martin,Claudia S. Moy,Robert Silbergleit,Thorsten Steiner,Jose I. Suarez,Kazunori Toyoda,Yongjun Wang,Haruko Yamamoto,Byung Woo Yoon +13 more
TLDR
The treatment of participants with intracerebral hemorrhage to achieve a target systolic blood pressure of 110 to 139mm Hg did not result in a lower rate of death or disability than standard reduction to a target of 140 to 179 mm Hg.Abstract:
BackgroundLimited data are available to guide the choice of a target for the systolic blood-pressure level when treating acute hypertensive response in patients with intracerebral hemorrhage. MethodsWe randomly assigned eligible participants with intracerebral hemorrhage (volume, <60 cm3) and a Glasgow Coma Scale (GCS) score of 5 or more (on a scale from 3 to 15, with lower scores indicating worse condition) to a systolic blood-pressure target of 110 to 139 mm Hg (intensive treatment) or a target of 140 to 179 mm Hg (standard treatment) in order to test the superiority of intensive reduction of systolic blood pressure to standard reduction; intravenous nicardipine to lower blood pressure was administered within 4.5 hours after symptom onset. The primary outcome was death or disability (modified Rankin scale score of 4 to 6, on a scale ranging from 0 [no symptoms] to 6 [death]) at 3 months after randomization, as ascertained by an investigator who was unaware of the treatment assignments. ResultsAmong 1000...read more
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2018 ESC/ESH Guidelines for the management of arterial hypertension.
B. Williams,G. Mancia,Wilko Spiering,Agabiti Rosei E,M. Azizi,Michel Burnier,Denis Clement,A. Coca,de Simone G,A Dominiczak,T. Kahan,Felix Mahfoud,Josep Redon,L.M. Ruilope,Alberto Zanchetti,Mary Kerins,S.E. Kjeldsen,Reinhold Kreutz,S. Laurent,Lip Gyh.,Richard J McManus,Krzysztof Narkiewicz,Frank Ruschitzka,R.E. Schmieder,Evgeny Shlyakhto,Constantinos Tsioufis,Aboyans,Ileana Desormais +27 more
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2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Paul K. Whelton,Robert M. Carey,Wilbert S. Aronow,Donald E. Casey,Karen J. Collins,Cheryl Dennison Himmelfarb,Sondra M. DePalma,Samuel S. Gidding,Kenneth Jamerson,Daniel W. Jones,Eric J. MacLaughlin,Paul Muntner,Bruce Ovbiagele,Sidney C. Smith,Crystal C. Spencer,Randall S. Stafford,Sandra J. Taler,Randal J. Thomas,Kim A. Williams,Jeff D. Williamson,Jackson T. Wright +20 more
TL;DR: Since 1980, the American College of Cardiology and American Heart Association have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health.
Journal ArticleDOI
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Paul K. Whelton,Robert M. Carey,Wilbert S. Aronow,Donald E. Casey,Karen J. Collins,Cheryl Dennison Himmelfarb,Sondra M. DePalma,Samuel S. Gidding,Kenneth Jamerson,Daniel W. Jones,Eric J. MacLaughlin,Paul Muntner,Bruce Ovbiagele,Sidney C. Smith,Crystal C. Spencer,Randall S. Stafford,Sandra J. Taler,Randal J. Thomas,Kim A. Williams,Jeff D. Williamson,Jackson T. Wright +20 more
TL;DR: The next generation of scientists and decision-makers will have a greater understanding of what constitutes a credible threat to public health and how to protect them from that threat.
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2018 ESC/ESH Guidelines for the management of arterial hypertension : The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension
Bryan Williams,Giuseppe Mancia,Wilko Spiering,Enrico Agabiti Rosei,Michel Azizi,Michel Burnier,Denis Clement,Antonio Coca,Giovanni de Simone,Anna F. Dominiczak,Thomas Kahan,Felix Mahfoud,Josep Redon,Luis M. Ruilope,Alberto Zanchetti,Mary Kerins,Sverre E. Kjeldsen,Reinhold Kreutz,Stéphane Laurent,Gregory Y.H. Lip,Richard J McManus,Krzysztof Narkiewicz,Frank Ruschitzka,Roland E. Schmieder,Evgeny Shlyakhto,Costas Tsioufis,Victor Aboyans,Ileana Desormais +27 more
TL;DR: De Backer et al. as mentioned in this paper developed the ESC Guidelines for the ESC Review Co-ordinator, which are used for the evaluation of the ESC review process and the review process.
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The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
Satoshi Umemura,Hisatomi Arima,Shuji Arima,Kei Asayama,Yasuaki Dohi,Yoshitaka Hirooka,Takeshi Horio,Satoshi Hoshide,Shunya Ikeda,Toshihiko Ishimitsu,Masaaki Ito,Sadayoshi Ito,Yoshio Iwashima,Hisashi Kai,Kei Kamide,Yoshihiko Kanno,Naoki Kashihara,Yuhei Kawano,Toru Kikuchi,Kazuo Kitamura,Takanari Kitazono,Katsuhiko Kohara,Masataka Kudo,Hiroo Kumagai,Kiyoshi Matsumura,Hideo Matsuura,Katsuyuki Miura,Masashi Mukoyama,Satoko Nakamura,Takayoshi Ohkubo,Yusuke Ohya,Takafumi Okura,Hiromi Rakugi,Shigeyuki Saitoh,Hirotaka Shibata,Tatsuo Shimosawa,Hiromichi Suzuki,Shori Takahashi,Kouichi Tamura,Hirofumi Tomiyama,Takuya Tsuchihashi,Shinichiro Ueda,Yoshinari Uehara,Hidenori Urata,Nobuhito Hirawa +44 more
TL;DR: The story of the life and times of Toshihiko Umemura and his family in the years leading up to and including his death.
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Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage
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TL;DR: In patients with intracerebral hemorrhage, intensive lowering of blood pressure did not result in a significant reduction in the rate of the primary outcome of death or severe disability, and an ordinal analysis of modified Rankin scores indicated improved functional outcomes with intensive loweringof blood pressure.
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