Journal ArticleDOI
Intermolecular interactions governing solubilization in micelles of poly(alkylene oxide) surfactants
TLDR
Partition coefficients for 39 low-molecular-mass compounds between water and micelles of an ethylene oxide-propylene oxide block copolymer (Pluronic P85) and the monolauryl ether of poly(ethylene oxide) (Brij 35) have been measured by the methods of fluorescence spectroscopy, fluorescence anisotropy, and dialysis kinetics as mentioned in this paper.Abstract:
Partition coefficients for 39 low-molecular-mass compounds between water and micelles of an ethylene oxide-propylene oxide block copolymer (Pluronic P85) and the monolauryl ether of poly(ethylene oxide) (Brij 35) have been measured by the methods of fluorescence spectroscopy, fluorescence anisotropy, and dialysis kinetics. The tested compounds include aromatic hydrocarbons, phenols, naphthols, xanthene dyes, anthracycline antibiotics, and porphyrins. The multifactor analysis of the partition coefficients in terms of the linear free-energy relationships has been performed. It has been shown that the H-donating ability of compounds facilitates their solubilization in Pluronic micelles and has no effect on solubilization in micelles of monolauryl ether of poly(ethylene oxide). This difference indicates that, when solubilization occurs in Pluronic micelles, the compounds under study appear in a hydrophobic core composed of poly(propylene oxide) blocks.read more
Citations
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Journal ArticleDOI
Polymeric micelles: authoritative aspects for drug delivery
TL;DR: Up-to-date review on important aspects of polymeric micelles, especially on the recent developments in the targetability of certain tissues such as cancerous tissues using polymeric mouselles are emphasized.
Journal ArticleDOI
Controlled release of volatile fragrance molecules from PEO-b-PPO-b-PEO block copolymer micelles in ethanol-water mixtures.
Damien Berthier,Isabelle Schmidt,Isabelle Schmidt,Wolfgang Fieber,Christophe Schatz,Christophe Schatz,Anton Furrer,Kenneth Wong,Sébastien Lecommandoux,Sébastien Lecommandoux +9 more
TL;DR: Active materials that can solubilize in different compartments of a sample show release properties which might be of interest in some applications where a delayed release of solutes for instance is required.
Journal ArticleDOI
The Effect of Pluronics on the Photocatalytic Activity of Water-Soluble Porphyrins
T. M. Zhientaev,N. S. Melik-Nubarov,E. A. Litmanovich,N. A. Aksenova,N. N. Glagolev,A. B. Solov’eva +5 more
TL;DR: In this article, the photocatalytic activity of porphyrins in the course of the oxidation of L-tryptophan in aqueous salt-containing solutions was investigated.
Journal ArticleDOI
Development of novel formulations for photodynamic therapy on the basis of amphiphilic polymers and porphyrin photosensitizers. Porphyrin-polymer complexes in model photosensitized processes
N. A. Aksenova,T. Oles,T. Sarna,N. N. Glagolev,A. V. Chernjak,V. I. Volkov,Svetlana L. Kotova,N. S. Melik-Nubarov,Anna B. Solovieva +8 more
TL;DR: In this article, the effect of amphiphilic polymers with different structure (polyvinylpyrrolidone, polyethyleneoxide and a triblock copolymer of ethylene-and propyleneoxide) on the photoactivity of a hematoporphyrin derivative (dimegin) was studied.
Journal ArticleDOI
Solubilization and location of phenol and benzene in a nonlinear amphiphilic EO–PO block copolymer micelles: 1H NMR and SANS studies
TL;DR: In this paper, the aqueous solution behavior of a poly(ethylene oxide)-poly(propylene oxide), PEO-PPO, star block copolymer Tetronic® T904 with solubilized phenol and benzene was examined by cloud point (CP), viscosity measurements, 1D and 2D NMR experiments, dynamic light scattering(DLS), and small angle neutron scattering (SANS) techniques.
References
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