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Journal ArticleDOI

Laser Reflectance Imaging of Human Chest for Localization of Internal Organs

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TLDR
To visualize the various tissues in lower regions of the thorax, the color-coded scheme of the NBI variation, as measured by the third fiber, is further expanded and the outlines of the heart and lungs are observed, which is in good agreement with that as determined by the chest radiographs taken in PA position.
Abstract
The normalized backscattered intensity (NBI) profiles at various locations of human thorax by multiprobe laser reflectometer are obtained. These data after digitization, interpolation, and filtering are color-coded and displayed as images on the outline of the human thorax. For optical characterization of tissues in terms of their parameters, scattering and absorption coefficients and the anisotropy parameter (g) are obtained by matching the measured NBI profile with that as obtained by Monte Carlo simulation procedure. Corresponding to the variation of the NBI over the various regions, the optical parameters show their respective changes. The maximum absorption and minimum scattering coefficients are observed at the areola, clavicle, sternum, scapula, and vertebral column. The minimum absorption and maximum scattering coefficients are observed at the pectoralis major of chest and rectus abdominis of abdomen regions, as compared to the other regions, attributed to their tissue compositional variations. To visualize the various tissues in lower regions of the thorax, the color-coded scheme of the NBI variation, as measured by the third fiber, is further expanded. By this procedure, the outlines of the heart and lungs, as detected through intercostals regions, are observed, which is in good agreement with that as determined by the chest radiograph of the same subject taken in PA position. Similarly the lower sections of the liver and stomach, due to their distinct optical parameters, are also observed.

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Citations
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Patent

Systems, apparatus and methods for tissue dissection

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Detection of Tumour in Biological Tissues by Laser Backscattering and Transillumination Signal Analysis

TL;DR: In this article, Monte Carlo simulation of the diffuse surface reflectance and transmittance for detection of the inhomogeneities/tumour in control tissue is carried out from the isolated heart, spleen and adipose tissues of goat digital phantoms.
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Simulation of laser backscattering system for imaging of inhomogeneity/tumor in biological tissues

TL;DR: The present simulated system not only shows the presence of inhomogeneties at various depths in tissue phantom but also presents their characteristics.
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Optical parameters of embedded abnormalities in tissues as determined by Monte Carlo simulation.

TL;DR: This study shows that depending on the type of embedded tissue the backscattered fraction as measured at 2 mm from the input fiber is altered and is enhanced for adipose and decreased for spleen tissue.
References
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Journal ArticleDOI

Tissue Characterization by Quantitative Optical Imaging Methods

TL;DR: A method for quantifying parameters of anomalous sites in breast tissue that may be used for functional characterization of tumors and a method which uses time-resolved data and capitalizes on probe lifetime sensitivity to metabolic parameters such as pH and temperature to obtain functional information from the tumor site.
Journal Article

Optical characterization and imaging of biological tissues

TL;DR: The structural variation in healthy and diseased tissues are determined and their relevance to early detection of tumour in tissues is discussed.
Journal ArticleDOI

Laser reflectance imaging of human forearms and their tissue-equivalent phantoms

TL;DR: The matching of the NBI images of these stable and inexpensive phantoms with those of the forearms of the respective subjects showed the similarity of their optical parameters.
Journal ArticleDOI

Optical characterization of mammalian tissues by laser reflectometry and Monte Carlo simulation

TL;DR: The optical characterization of various goat organs/tissues, by measurement of the spatial variation of the diffuse reflectance from the surface by laser multi-probe reflectometer, is carried out by matching iterative procedures with Monte Carlo simulation by best-fit procedure.
Journal Article

Optical imaging and parametric characterization of frostbite changes in human hand tissues

TL;DR: The optical parameters, absorption and scattering coefficients, as determined by matching of the measured surface profile with that as obtained by Monte Carlo simulation of photon-scattering process, show an increase in absorption coefficient and decrease in scattering coefficient of the frostbite-affected tissues compared to those of control subjects.
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