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Journal ArticleDOI

Laser Reflectance Imaging of Human Chest for Localization of Internal Organs

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TLDR
To visualize the various tissues in lower regions of the thorax, the color-coded scheme of the NBI variation, as measured by the third fiber, is further expanded and the outlines of the heart and lungs are observed, which is in good agreement with that as determined by the chest radiographs taken in PA position.
Abstract
The normalized backscattered intensity (NBI) profiles at various locations of human thorax by multiprobe laser reflectometer are obtained. These data after digitization, interpolation, and filtering are color-coded and displayed as images on the outline of the human thorax. For optical characterization of tissues in terms of their parameters, scattering and absorption coefficients and the anisotropy parameter (g) are obtained by matching the measured NBI profile with that as obtained by Monte Carlo simulation procedure. Corresponding to the variation of the NBI over the various regions, the optical parameters show their respective changes. The maximum absorption and minimum scattering coefficients are observed at the areola, clavicle, sternum, scapula, and vertebral column. The minimum absorption and maximum scattering coefficients are observed at the pectoralis major of chest and rectus abdominis of abdomen regions, as compared to the other regions, attributed to their tissue compositional variations. To visualize the various tissues in lower regions of the thorax, the color-coded scheme of the NBI variation, as measured by the third fiber, is further expanded. By this procedure, the outlines of the heart and lungs, as detected through intercostals regions, are observed, which is in good agreement with that as determined by the chest radiograph of the same subject taken in PA position. Similarly the lower sections of the liver and stomach, due to their distinct optical parameters, are also observed.

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Citations
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In Vivo Endoscopic Optical Biopsy with Optical Coherence Tomography

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Patent

Systems, apparatus and methods for tissue dissection

TL;DR: In this article, a method for tissue dissection and testing may comprise inserting a tissue dissecting wand (TD) through an incision in a patient's body and then separating tissue using the lysing segment(s) to access a target region, the sensor may be activated and moved around within the target region to assess tissues.
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Detection of Tumour in Biological Tissues by Laser Backscattering and Transillumination Signal Analysis

TL;DR: In this article, Monte Carlo simulation of the diffuse surface reflectance and transmittance for detection of the inhomogeneities/tumour in control tissue is carried out from the isolated heart, spleen and adipose tissues of goat digital phantoms.
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Simulation of laser backscattering system for imaging of inhomogeneity/tumor in biological tissues

TL;DR: The present simulated system not only shows the presence of inhomogeneties at various depths in tissue phantom but also presents their characteristics.
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Optical parameters of embedded abnormalities in tissues as determined by Monte Carlo simulation.

TL;DR: This study shows that depending on the type of embedded tissue the backscattered fraction as measured at 2 mm from the input fiber is altered and is enhanced for adipose and decreased for spleen tissue.
References
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Journal ArticleDOI

Laser-Induced Fluorescence and Reflectance Spectroscopy for the Discrimination of Basal Cell Carcinoma from the Surrounding Normal Skin Tissue

TL;DR: It seems that LIF and reflectance spectra could be used to differentiate neoplastic from normal skin tissue using an appropriate classification model analysis.
Journal Article

High resolution optical tomographic imaging of soft biological tissues

TL;DR: The application of the OCT system to image soft biological tissues with resolution approaching 9 microns is reported, providing information on tissue microstructure that could only previously be obtained with conventional excisional biopsy.
Journal ArticleDOI

Characterization and imaging of compositional variation in tissues

TL;DR: The diffuse surface reflectance profiles of the goat's isolated heart, spleen, and adipose tissues by multiprobe laser reflectometer are measured and the type, location, and size of the tissue compositional variation are determined.
Journal ArticleDOI

Optical non-invasive technique for vessel imaging: I. Experimental results.

TL;DR: Experimental results indicate that the vessel imaging facility depends upon source-detector separation, relative position and vessel depth, and does not depend essentially on the radiant power from the light source, and it is shown that a proper choice of probe parameters can improve the vessel identification ability.
Proceedings ArticleDOI

Diagnosis of inflammatory rheumatic diseases with photon density waves

TL;DR: Investigations for optical diagnostics using photon density waves (PDW) indicated a significant pathological increase in synovia and synovialis of healthy and early RA stages and provided a sufficient spatial resolution in order to assign functional changes to anatomical structures.
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