Journal ArticleDOI
Lesions on the back of hands and female gender predispose to stigmatization in patients with psoriasis
Marlena Hawro,Marcus Maurer,Karsten Weller,Romuald Maleszka,Anna Zalewska-Janowska,Andrzej Kaszuba,Zofia Gerlicz-Kowalczuk,Tomasz Hawro +7 more
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TLDR
Psoriatic lesions on the back of hands are debilitating and warrant effective treatment and special attention should be paid to female patients, who are more sensitive to stigmatization.Abstract:
Background Psoriasis vulgaris is characterized by disfiguring and stigmatizing skin lesions. The links among lesions distribution, severity, and stigmatization remain unclear. Objective We sought to investigate if the involvement of visible and sensitive areas is linked to stigmatization. Methods In all, 115 patients with psoriasis vulgaris were assessed for disease severity, skin lesions distribution, itch, and stigmatization using the Feelings of Stigmatization Questionnaire. Quality of life was assessed with the Dermatology Life Quality Index and the World Health Organization Quality of Life-BREF. Results The localization of psoriatic lesions on the back of hands was related to higher stigmatization levels ( P = .011, total score of the Feelings of Stigmatization Questionnaire), but not the involvement of nails, the palms, the face, or the genital area nor overall disease severity. All patients reported some level of stigmatization, regardless of the localization of lesions and type of psoriasis. Higher levels of stigmatization characterized patients who claimed not to be able to hide their lesions by clothing ( P = .025), women ( P = .001), and the unemployed ( P = .004). Stigmatization was the strongest predictor of quality of life impairment. Limitations Only hospitalized patients were included. Conclusions Psoriatic lesions on the back of hands are debilitating and warrant effective treatment. Special attention should be paid to female patients, who are more sensitive to stigmatization.read more
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Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities
Craig A. Elmets,Craig L. Leonardi,Dawn Marie R. Davis,Joel M. Gelfand,Jason Lichten,Nehal N. Mehta,April W. Armstrong,Cody Connor,Kelly M. Cordoro,Boni E. Elewski,Kenneth B. Gordon,Alice B. Gottlieb,Daniel H. Kaplan,Arthur Kavanaugh,Dario Kivelevitch,Matthew Kiselica,Neil J. Korman,Daniela Kroshinsky,Mark Lebwohl,Henry W. Lim,Amy S. Paller,Sylvia L. Parra,Arun L. Pathy,Elizabeth Farley Prater,Reena N. Rupani,Michael Siegel,Benjamin K. Stoff,Bruce Strober,Emily B. Wong,Jashin J. Wu,Vidhya Hariharan,Alan Menter +31 more
TL;DR: In this article, the authors address important clinical questions that arise in psoriasis management and care, providing recommendations on the basis of available evidence, and provide recommendations based on available evidence.
Journal ArticleDOI
The Urticaria Activity Score—Validity, Reliability, and Responsiveness
Tomasz Hawro,Tatevik Ohanyan,Nicole Schoepke,Martin Metz,Adriane Peveling-Oberhag,Petra Staubach,Marcus Maurer,Karsten Weller +7 more
TL;DR: The Uas7 and UAS7TD show good and comparable clinimetric properties, including good sensitivity to change, and similar MIDs.
Journal ArticleDOI
Differential efficacy of biologic treatments targeting the TNF-α/IL-23/IL-17 axis in psoriasis and psoriatic arthritis
TL;DR: Given that the IL‐17 signature is more upregulated in the skin than in synovium in psoriatic arthritis, anti‐IL‐23/IL‐17 agents seem to be superior to anti‐TNF‐&agr; remedies in the treatment of skin lesions.
Journal ArticleDOI
Autoimmunity and autoimmune co-morbidities in psoriasis.
TL;DR: The recent topics on autoimmunity and autoimmune co‐morbidities in psoriasis are reviewed.
Journal ArticleDOI
Psoriasis and the TNF/IL23/IL17 axis
TL;DR: Recent topics in psoriasis and the TNF/IL23/IL17 axis are summarized and anti-IL-23/ IL-17 agents seem to be superior to anti-TNF-α remedies in the treatment of skin lesions.
References
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Journal ArticleDOI
Stigma: Notes on the Management of Spoiled Identity.
Melvin L. DeFleur,Erving Goffman +1 more
TL;DR: In this article, the authors discuss the relationship between information control and personal identity, including the Discredited and the Discreditable Social Information Visibility Personal Identity Biography Biographical Others Passing Techniques of Information Control Covering.
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Stigma: Notes on the Management of Spoiled Identity
TL;DR: In this article, the authors discuss the relationship between information control and personal identity, including the Discredited and the Discreditable Social Information Visibility Personal Identity Biography Biographical Others Passing Techniques of Information Control Covering.
Journal ArticleDOI
Dermatology Life Quality Index (DLQI)—a simple practical measure for routine clinical use
Andrew Yule Finlay,G. K. Khan +1 more
TL;DR: This study confirmed that a topic eczema, psoriasis and generalized pruritus have a greater impact on quality of life than acne, basal cell carcinomas and viral warts.
Journal ArticleDOI
The World Health Organization's WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. A report from the WHOQOL group.
TL;DR: Overall, the WHOQOL-BREF is a sound, cross-culturally valid assessment of QOL, as reflected by its four domains: physical, psychological, social and environment.
Journal ArticleDOI
Evolutionary origins of stigmatization: the functions of social exclusion.
Robert Kurzban,Mark R. Leary +1 more
TL;DR: The authors propose that phenomena currently placed under the general rubric of stigma involve a set of distinct psychological systems designed by natural selection to solve specific problems associated with sociality.
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