Journal ArticleDOI
Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins.
Alejandra Lazzaro,Montserrat Corominas,Cristina Martí,Cristina Flors,Laura R. Izquierdo,Teresa A. Grillo,Javier G. Luis,Santi Nonell +7 more
Reads0
Chats0
TLDR
The light-induced singlet oxygen production and antifungal activity of phenylphenalenone phytoalexins isolated from infected banana plants are reported and the correlation of IC50 values under illumination with the quantum yield of singletoxy production and the enhancing effect of D2O on the antifundal activity are suggested.Abstract:
The light-induced singlet oxygen production and antifungal activity of phenylphenalenone phytoalexins isolated from infected banana plants (Musa acuminata) are reported. Upon absorption of light energy all studied phenylphenalenones sensitise the production of singlet oxygen in polar and non-polar media. Antifungal activity of these compounds towards Fusarium oxysporum is enhanced in the presence of light. These results, together with the correlation of IC50 values under illumination with the quantum yield of singlet oxygen production and the enhancing effect of D2O on the antifungal activity, suggest the intermediacy of singlet oxygen produced by electronic excitation of the phenylphenalenone phytoalexins.read more
Citations
More filters
Journal ArticleDOI
Imaging the production of singlet oxygen in vivo using a new fluorescent sensor, Singlet Oxygen Sensor Green®
Cristina Flors,Michael J. Fryer,Jen Waring,Brandon J. Reeder,Ulrike Bechtold,Philip M. Mullineaux,Santi Nonell,Michael T. Wilson,Neil R. Baker +8 more
TL;DR: SOSG is a useful in vivo probe for the detection of singlet oxygen, which is thought to have a very short half-life in biological systems and, consequently, it is difficult to detect.
Journal ArticleDOI
Light and singlet oxygen in plant defense against pathogens: phototoxic phenalenone phytoalexins.
Cristina Flors,Santi Nonell +1 more
TL;DR: The occurrence of phenalenone chromophores in phytoalexins of plants originally nonphototoxic suggests that these plants respond to pathogen attacks by biosynthesizing singlet oxygen photosensitizers able to use solar energy for defense.
Journal ArticleDOI
The photoactivity of natural products - An overlooked potential of phytomedicines?
Bianka Siewert,Hermann Stuppner +1 more
TL;DR: A systematic review of reported natural photosensitizers and their supposed medicinal application was conducted by employing PubMed, Scifinder, and Web of Science as discussed by the authors, including information about their natural sources, their photoyield, and their pharmacological application.
Journal ArticleDOI
Photodynamic inactivation as an emergent strategy against foodborne pathogenic bacteria in planktonic and sessile states.
Alex Fiori da Silva,Alex Fiori da Silva,Anabela Borges,Efstathios Giaouris,Jane Martha Graton Mikcha,Manuel Simões +5 more
TL;DR: Antimicrobial photodynamic therapy (aPDT) has become a novel alternative for controlling foodborne pathogenic bacteria in both planktonic and sessile states and it is less likely to cause antimicrobial resistance and it does not promote undesirable nutritional and sensory changes in the food matrix.
Journal ArticleDOI
Phototoxic phytoalexins. Processes that compete with the photosensitized production of singlet oxygen by 9-phenylphenalenones.
Cristina Flors,Peter R. Ogilby,Javier G. Luis,Teresa A. Grillo,Laura R. Izquierdo,Pier-Luigi Gentili,Laura Bussotti,Santi Nonell +7 more
TL;DR: Evidence of an intramolecular charge-transfer process in the excited singlet and the triplet states of 9-phenylphenalenones that modulates the photosensitized production of singlet oxygen is provided.
References
More filters
Journal ArticleDOI
Plant pathogens and integrated defence responses to infection.
TL;DR: The current knowledge of recognition-dependent disease resistance in plants is reviewed, and a few crucial concepts are included to compare and contrast plant innate immunity with that more commonly associated with animals.
Journal ArticleDOI
Physical mechanisms of generation and deactivation of singlet oxygen.
TL;DR: Reactions of O2(∆g) are associated with significant applications in several fields, including organic synthesis, bleaching processes, and, most importantly, the photodynamic therapy of cancer, which has now obtained regulatory approval in most countries for the treatment of several types of tumors.
Journal ArticleDOI
Natural products and plant disease resistance
TL;DR: Genetic and reverse genetic approaches are providing evidence for the importance of natural products in host defence, and metabolic engineering of natural product pathways is now a feasible strategy for enhancement of plant disease resistance.
Journal ArticleDOI
Gene silencing as an adaptive defence against viruses
TL;DR: Gene silencing was perceived initially as an unpredictable and inconvenient side effect of introducing transgenes into plants but it now seems that it is the consequence of accidentally triggering the plant's adaptive defence mechanism against viruses and transposable elements.
Journal ArticleDOI
Programmed cell death, mitochondria and the plant hypersensitive response
TL;DR: Many of the cell-death regulators that have been characterized in humans, worms and flies are absent from the Arabidopsis genome, indicating that plants probably use other regulators to control this process.
Related Papers (5)
Light and singlet oxygen in plant defense against pathogens: phototoxic phenalenone phytoalexins.
Cristina Flors,Santi Nonell +1 more
Phenalenone-type phytoalexins mediate resistance of banana plants (Musa spp.) to the burrowing nematode Radopholus similis
Dirk Hölscher,Suganthagunthalam Dhakshinamoorthy,Theodore Alexandrov,Michael Becker,Tom Bretschneider,Andreas Buerkert,Anna C. Crecelius,Dirk De Waele,Dirk De Waele,Annemie Elsen,David G. Heckel,Heike Heklau,Christian Hertweck,Marco Kai,Katrin Knop,Christoph Krafft,Ravi Kumar Maddula,Christian Matthäus,Jürgen Popp,Jürgen Popp,Bernd Schneider,Ulrich S. Schubert,Richard A. Sikora,Aleš Svatoš,Rony Swennen +24 more